Mouse Thioredoxin Gene Maps on Chromosome 4, whereas Its Pseudogene Maps on Chromosome 1

Makoto Taketo, Minoru Matsui, Julie M. Rochelle, Junji Yodoi, Michael F Seldin

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

Thioredoxins are involved in various biochemical systems and mediate both redox and nonredox functions. In mammalian cells, thioredoxin functions as an endogenous glucocorticoid receptor activating factor and as an adult T-cell leukemia-derived factor (ADF) that stimulates expression of interleukin-2 receptor in human T-cell leukemia virus (HTLV)-I transformed T cells. We have mapped the thioredoxin gene (Txn) and its processed pseudogene (Txn-ps1) in the mouse using a panel of interspecific backcross mice. Txn maps to Chr 4, whereas Txn-ps1 maps to the proximal region of Chr 1.

Original languageEnglish (US)
Pages (from-to)251-253
Number of pages3
JournalGenomics
Volume21
Issue number1
DOIs
StatePublished - May 1 1994
Externally publishedYes

Fingerprint

Chromosomes, Human, Pair 4
Pseudogenes
Thioredoxins
Chromosomes, Human, Pair 1
Genes
Human T-lymphotropic virus 1
Interleukin-2 Receptors
Glucocorticoid Receptors
Oxidation-Reduction
T-Lymphocytes

ASJC Scopus subject areas

  • Genetics

Cite this

Mouse Thioredoxin Gene Maps on Chromosome 4, whereas Its Pseudogene Maps on Chromosome 1. / Taketo, Makoto; Matsui, Minoru; Rochelle, Julie M.; Yodoi, Junji; Seldin, Michael F.

In: Genomics, Vol. 21, No. 1, 01.05.1994, p. 251-253.

Research output: Contribution to journalArticle

Taketo, Makoto ; Matsui, Minoru ; Rochelle, Julie M. ; Yodoi, Junji ; Seldin, Michael F. / Mouse Thioredoxin Gene Maps on Chromosome 4, whereas Its Pseudogene Maps on Chromosome 1. In: Genomics. 1994 ; Vol. 21, No. 1. pp. 251-253.
@article{65cdaaac972f4189bd6cebd2f310429c,
title = "Mouse Thioredoxin Gene Maps on Chromosome 4, whereas Its Pseudogene Maps on Chromosome 1",
abstract = "Thioredoxins are involved in various biochemical systems and mediate both redox and nonredox functions. In mammalian cells, thioredoxin functions as an endogenous glucocorticoid receptor activating factor and as an adult T-cell leukemia-derived factor (ADF) that stimulates expression of interleukin-2 receptor in human T-cell leukemia virus (HTLV)-I transformed T cells. We have mapped the thioredoxin gene (Txn) and its processed pseudogene (Txn-ps1) in the mouse using a panel of interspecific backcross mice. Txn maps to Chr 4, whereas Txn-ps1 maps to the proximal region of Chr 1.",
author = "Makoto Taketo and Minoru Matsui and Rochelle, {Julie M.} and Junji Yodoi and Seldin, {Michael F}",
year = "1994",
month = "5",
day = "1",
doi = "10.1006/geno.1994.1252",
language = "English (US)",
volume = "21",
pages = "251--253",
journal = "Genomics",
issn = "0888-7543",
publisher = "Academic Press Inc.",
number = "1",

}

TY - JOUR

T1 - Mouse Thioredoxin Gene Maps on Chromosome 4, whereas Its Pseudogene Maps on Chromosome 1

AU - Taketo, Makoto

AU - Matsui, Minoru

AU - Rochelle, Julie M.

AU - Yodoi, Junji

AU - Seldin, Michael F

PY - 1994/5/1

Y1 - 1994/5/1

N2 - Thioredoxins are involved in various biochemical systems and mediate both redox and nonredox functions. In mammalian cells, thioredoxin functions as an endogenous glucocorticoid receptor activating factor and as an adult T-cell leukemia-derived factor (ADF) that stimulates expression of interleukin-2 receptor in human T-cell leukemia virus (HTLV)-I transformed T cells. We have mapped the thioredoxin gene (Txn) and its processed pseudogene (Txn-ps1) in the mouse using a panel of interspecific backcross mice. Txn maps to Chr 4, whereas Txn-ps1 maps to the proximal region of Chr 1.

AB - Thioredoxins are involved in various biochemical systems and mediate both redox and nonredox functions. In mammalian cells, thioredoxin functions as an endogenous glucocorticoid receptor activating factor and as an adult T-cell leukemia-derived factor (ADF) that stimulates expression of interleukin-2 receptor in human T-cell leukemia virus (HTLV)-I transformed T cells. We have mapped the thioredoxin gene (Txn) and its processed pseudogene (Txn-ps1) in the mouse using a panel of interspecific backcross mice. Txn maps to Chr 4, whereas Txn-ps1 maps to the proximal region of Chr 1.

UR - http://www.scopus.com/inward/record.url?scp=0028363443&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0028363443&partnerID=8YFLogxK

U2 - 10.1006/geno.1994.1252

DO - 10.1006/geno.1994.1252

M3 - Article

VL - 21

SP - 251

EP - 253

JO - Genomics

JF - Genomics

SN - 0888-7543

IS - 1

ER -