Mortality During Total Hip Periprosthetic Joint Infection

Kyle M. Natsuhara; Trevor J. Shelton; John Meehan; Zachary C. Lum

doi:10.1016/j.arth.2018.12.024

Mortality During Total Hip Periprosthetic Joint Infection

Kyle M. Natsuhara, Trevor J. Shelton, John Meehan, Zachary C. Lum

Orthopaedic Surgery

Research output: Contribution to journal › Article › peer-review

19 Scopus citations

Abstract

Background: We sought to understand the mortality rate of periprosthetic joint infection (PJI) of the hip undergoing 2-stage revision for infection. Methods: Database search, yielding 23 relevant studies, totaled 19,169 patients who underwent revision for total hip PJI. Results: One-year weighted mortality rate was 4.22% after total hip PJI. Five-year mortality was 21.12%. Average age was 65 years. When comparing the national age-adjusted risk of mortality and the reported 1-year mortality risk in this systematic review, the risk of death after total hip PJI is significantly increased (odds ratio 3.58, P <.001). Conclusion: The mortality rate during total hip revision for infection is high. When counseling a patient regarding complications of this disease, death should be discussed.

Original language	English (US)
Journal	Journal of Arthroplasty
DOIs	https://doi.org/10.1016/j.arth.2018.12.024
State	Accepted/In press - Jan 1 2019

Keywords

2-stage revision arthroplasty
mortality after total hip arthroplasty periprosthetic joint infection
periprosthetic joint infection
prosthetic joint infection
total hip arthroplasty

ASJC Scopus subject areas

Orthopedics and Sports Medicine

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10.1016/j.arth.2018.12.024

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Cite this

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title = "Mortality During Total Hip Periprosthetic Joint Infection",

abstract = "Background: We sought to understand the mortality rate of periprosthetic joint infection (PJI) of the hip undergoing 2-stage revision for infection. Methods: Database search, yielding 23 relevant studies, totaled 19,169 patients who underwent revision for total hip PJI. Results: One-year weighted mortality rate was 4.22% after total hip PJI. Five-year mortality was 21.12%. Average age was 65 years. When comparing the national age-adjusted risk of mortality and the reported 1-year mortality risk in this systematic review, the risk of death after total hip PJI is significantly increased (odds ratio 3.58, P <.001). Conclusion: The mortality rate during total hip revision for infection is high. When counseling a patient regarding complications of this disease, death should be discussed.",

keywords = "2-stage revision arthroplasty, mortality after total hip arthroplasty periprosthetic joint infection, periprosthetic joint infection, prosthetic joint infection, total hip arthroplasty",

author = "Natsuhara, {Kyle M.} and Shelton, {Trevor J.} and John Meehan and Lum, {Zachary C.}",

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doi = "10.1016/j.arth.2018.12.024",

language = "English (US)",

journal = "Journal of Arthroplasty",

issn = "0883-5403",

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T1 - Mortality During Total Hip Periprosthetic Joint Infection

AU - Natsuhara, Kyle M.

AU - Shelton, Trevor J.

AU - Meehan, John

AU - Lum, Zachary C.

PY - 2019/1/1

Y1 - 2019/1/1

N2 - Background: We sought to understand the mortality rate of periprosthetic joint infection (PJI) of the hip undergoing 2-stage revision for infection. Methods: Database search, yielding 23 relevant studies, totaled 19,169 patients who underwent revision for total hip PJI. Results: One-year weighted mortality rate was 4.22% after total hip PJI. Five-year mortality was 21.12%. Average age was 65 years. When comparing the national age-adjusted risk of mortality and the reported 1-year mortality risk in this systematic review, the risk of death after total hip PJI is significantly increased (odds ratio 3.58, P <.001). Conclusion: The mortality rate during total hip revision for infection is high. When counseling a patient regarding complications of this disease, death should be discussed.

AB - Background: We sought to understand the mortality rate of periprosthetic joint infection (PJI) of the hip undergoing 2-stage revision for infection. Methods: Database search, yielding 23 relevant studies, totaled 19,169 patients who underwent revision for total hip PJI. Results: One-year weighted mortality rate was 4.22% after total hip PJI. Five-year mortality was 21.12%. Average age was 65 years. When comparing the national age-adjusted risk of mortality and the reported 1-year mortality risk in this systematic review, the risk of death after total hip PJI is significantly increased (odds ratio 3.58, P <.001). Conclusion: The mortality rate during total hip revision for infection is high. When counseling a patient regarding complications of this disease, death should be discussed.

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KW - mortality after total hip arthroplasty periprosthetic joint infection

KW - periprosthetic joint infection

KW - prosthetic joint infection

KW - total hip arthroplasty

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