Morphological variation in the horse: Defining complex traits of body size and shape

S. A. Brooks, S. Makvandi-Nejad, E. Chu, J. J. Allen, C. Streeter, E. Gu, B. McCleery, B. A. Murphy, Rebecca Bellone, N. B. Sutter

Research output: Contribution to journalArticle

50 Citations (Scopus)

Abstract

Horses, like many domesticated species, have been selected for broad variation in skeletal size. This variation is not only an interesting model of rapid evolutionary change during domestication, but is also directly applicable to the horse industry. Breeders select for complex traits like body size and skeletal conformation to improve marketability, function, soundness and performance in the show ring. Using a well-defined set of 35 measurements, we have identified and quantified skeletal variation in the horse species. We collected measurements from 1215 horses representing 65 breeds of diverse conformation such as the American Miniature, Shetland Pony, Arabian Horse, Thoroughbred, Shire and Clydesdale. Principal components analysis has identified two key dimensions of skeletal variation in the horse. Principal component 1 is positively correlated with every measurement and quantifies overall body size. Principal component 2 captures a pattern of bone widths vs. lengths and thus quantifies variation in overall bone thickness. By defining these complex skeletal traits, we have created a framework for whole genome association studies to identify quantitative trait loci that contribute to this variation.

Original languageEnglish (US)
Pages (from-to)159-165
Number of pages7
JournalAnimal Genetics
Volume41
Issue numberSUPPL. 2
DOIs
StatePublished - Dec 1 2010
Externally publishedYes

Fingerprint

Body Size
anthropometric measurements
Horses
body size
horses
bones
Arabian (horse breed)
Bone and Bones
Quantitative Trait Loci
Genome-Wide Association Study
Principal Component Analysis
domestication
quantitative trait loci
Industry
principal component analysis
industry
breeds

Keywords

  • Complex trait
  • Horse
  • Morphology
  • Principal components analysis
  • Skeleton

ASJC Scopus subject areas

  • Genetics
  • Animal Science and Zoology
  • Medicine(all)

Cite this

Brooks, S. A., Makvandi-Nejad, S., Chu, E., Allen, J. J., Streeter, C., Gu, E., ... Sutter, N. B. (2010). Morphological variation in the horse: Defining complex traits of body size and shape. Animal Genetics, 41(SUPPL. 2), 159-165. https://doi.org/10.1111/j.1365-2052.2010.02127.x

Morphological variation in the horse : Defining complex traits of body size and shape. / Brooks, S. A.; Makvandi-Nejad, S.; Chu, E.; Allen, J. J.; Streeter, C.; Gu, E.; McCleery, B.; Murphy, B. A.; Bellone, Rebecca; Sutter, N. B.

In: Animal Genetics, Vol. 41, No. SUPPL. 2, 01.12.2010, p. 159-165.

Research output: Contribution to journalArticle

Brooks, SA, Makvandi-Nejad, S, Chu, E, Allen, JJ, Streeter, C, Gu, E, McCleery, B, Murphy, BA, Bellone, R & Sutter, NB 2010, 'Morphological variation in the horse: Defining complex traits of body size and shape', Animal Genetics, vol. 41, no. SUPPL. 2, pp. 159-165. https://doi.org/10.1111/j.1365-2052.2010.02127.x
Brooks SA, Makvandi-Nejad S, Chu E, Allen JJ, Streeter C, Gu E et al. Morphological variation in the horse: Defining complex traits of body size and shape. Animal Genetics. 2010 Dec 1;41(SUPPL. 2):159-165. https://doi.org/10.1111/j.1365-2052.2010.02127.x
Brooks, S. A. ; Makvandi-Nejad, S. ; Chu, E. ; Allen, J. J. ; Streeter, C. ; Gu, E. ; McCleery, B. ; Murphy, B. A. ; Bellone, Rebecca ; Sutter, N. B. / Morphological variation in the horse : Defining complex traits of body size and shape. In: Animal Genetics. 2010 ; Vol. 41, No. SUPPL. 2. pp. 159-165.
@article{047d90348d22454aa05f72ccca72cb3c,
title = "Morphological variation in the horse: Defining complex traits of body size and shape",
abstract = "Horses, like many domesticated species, have been selected for broad variation in skeletal size. This variation is not only an interesting model of rapid evolutionary change during domestication, but is also directly applicable to the horse industry. Breeders select for complex traits like body size and skeletal conformation to improve marketability, function, soundness and performance in the show ring. Using a well-defined set of 35 measurements, we have identified and quantified skeletal variation in the horse species. We collected measurements from 1215 horses representing 65 breeds of diverse conformation such as the American Miniature, Shetland Pony, Arabian Horse, Thoroughbred, Shire and Clydesdale. Principal components analysis has identified two key dimensions of skeletal variation in the horse. Principal component 1 is positively correlated with every measurement and quantifies overall body size. Principal component 2 captures a pattern of bone widths vs. lengths and thus quantifies variation in overall bone thickness. By defining these complex skeletal traits, we have created a framework for whole genome association studies to identify quantitative trait loci that contribute to this variation.",
keywords = "Complex trait, Horse, Morphology, Principal components analysis, Skeleton",
author = "Brooks, {S. A.} and S. Makvandi-Nejad and E. Chu and Allen, {J. J.} and C. Streeter and E. Gu and B. McCleery and Murphy, {B. A.} and Rebecca Bellone and Sutter, {N. B.}",
year = "2010",
month = "12",
day = "1",
doi = "10.1111/j.1365-2052.2010.02127.x",
language = "English (US)",
volume = "41",
pages = "159--165",
journal = "Animal Genetics",
issn = "0268-9146",
publisher = "Wiley-Blackwell",
number = "SUPPL. 2",

}

TY - JOUR

T1 - Morphological variation in the horse

T2 - Defining complex traits of body size and shape

AU - Brooks, S. A.

AU - Makvandi-Nejad, S.

AU - Chu, E.

AU - Allen, J. J.

AU - Streeter, C.

AU - Gu, E.

AU - McCleery, B.

AU - Murphy, B. A.

AU - Bellone, Rebecca

AU - Sutter, N. B.

PY - 2010/12/1

Y1 - 2010/12/1

N2 - Horses, like many domesticated species, have been selected for broad variation in skeletal size. This variation is not only an interesting model of rapid evolutionary change during domestication, but is also directly applicable to the horse industry. Breeders select for complex traits like body size and skeletal conformation to improve marketability, function, soundness and performance in the show ring. Using a well-defined set of 35 measurements, we have identified and quantified skeletal variation in the horse species. We collected measurements from 1215 horses representing 65 breeds of diverse conformation such as the American Miniature, Shetland Pony, Arabian Horse, Thoroughbred, Shire and Clydesdale. Principal components analysis has identified two key dimensions of skeletal variation in the horse. Principal component 1 is positively correlated with every measurement and quantifies overall body size. Principal component 2 captures a pattern of bone widths vs. lengths and thus quantifies variation in overall bone thickness. By defining these complex skeletal traits, we have created a framework for whole genome association studies to identify quantitative trait loci that contribute to this variation.

AB - Horses, like many domesticated species, have been selected for broad variation in skeletal size. This variation is not only an interesting model of rapid evolutionary change during domestication, but is also directly applicable to the horse industry. Breeders select for complex traits like body size and skeletal conformation to improve marketability, function, soundness and performance in the show ring. Using a well-defined set of 35 measurements, we have identified and quantified skeletal variation in the horse species. We collected measurements from 1215 horses representing 65 breeds of diverse conformation such as the American Miniature, Shetland Pony, Arabian Horse, Thoroughbred, Shire and Clydesdale. Principal components analysis has identified two key dimensions of skeletal variation in the horse. Principal component 1 is positively correlated with every measurement and quantifies overall body size. Principal component 2 captures a pattern of bone widths vs. lengths and thus quantifies variation in overall bone thickness. By defining these complex skeletal traits, we have created a framework for whole genome association studies to identify quantitative trait loci that contribute to this variation.

KW - Complex trait

KW - Horse

KW - Morphology

KW - Principal components analysis

KW - Skeleton

UR - http://www.scopus.com/inward/record.url?scp=78449309131&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=78449309131&partnerID=8YFLogxK

U2 - 10.1111/j.1365-2052.2010.02127.x

DO - 10.1111/j.1365-2052.2010.02127.x

M3 - Article

C2 - 21070291

AN - SCOPUS:78449309131

VL - 41

SP - 159

EP - 165

JO - Animal Genetics

JF - Animal Genetics

SN - 0268-9146

IS - SUPPL. 2

ER -