Morphogenesis of vesiculation in foot-and-mouth disease.

Tilahun Yilma

Research output: Contribution to journalArticle

20 Citations (Scopus)

Abstract

The morphogenesis of vesiculation in cattle inoculated (aerosol expsoure) with foot-and-mouth disease virus was investigated by examining alternate, frozen sections of selected tissues stained by fluorescent antibody technique and with hematoxylin and eosin. Viremia preceded the development of lesions, and virus appeared to be transported to the epithelium via papillae. Lesions were initiated usually by the infection of single cells in the stratum spinosum adjacent to the papillae. Three types of lesions were observed. A vesicle developed mainly from the lysis of swollen, spherical cells and the release of intracellular fluid. The 2nd type of lesion was formed mainly by the accumulation of intercellular edema. The 3rd type was characterized by the absence of a vesicle due to seepage and loss of edema fluid and desiccation of the lesion.

Original languageEnglish (US)
Pages (from-to)1537-1542
Number of pages6
JournalAmerican Journal of Veterinary Research
Volume41
Issue number9
StatePublished - Sep 1980
Externally publishedYes

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Foot-and-Mouth Disease
foot-and-mouth disease
Morphogenesis
lesions (animal)
morphogenesis
Edema
Intracellular Fluid
Foot-and-Mouth Disease Virus
Desiccation
Viremia
Frozen Sections
Hematoxylin
Eosine Yellowish-(YS)
Aerosols
Fluorescent Antibody Technique
Epithelium
edema
Viruses
Infection
Foot-and-mouth disease virus

ASJC Scopus subject areas

  • veterinary(all)

Cite this

Morphogenesis of vesiculation in foot-and-mouth disease. / Yilma, Tilahun.

In: American Journal of Veterinary Research, Vol. 41, No. 9, 09.1980, p. 1537-1542.

Research output: Contribution to journalArticle

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