Monitoring human exposure to pesticides using immunoassay

Marja E. Koivunen, Shirley J. Gee, Mikaela Nichkova, Ki Chang Ahn, Bruce D. Hammock

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Citations (Scopus)

Abstract

Immunoassays offer selective, sensitive and low-cost tools for the assessment of pesticide exposure through the measurement of parent compounds or key metabolites in biological fluids such as urine, blood or saliva. Recently conducted biomonitoring studies for paraquat and atrazine illustrate the strengths and weaknesses of the immunochemical approach. Development for improved assay throughput and sensitivity includes substitution of enzyme labels with fluorescent nanoparticle probes or luminescent acridinium labels together with the use of automated immunoanalyzers, immunosensors or microchips with flow-through systems.

Original languageEnglish (US)
Title of host publicationACS Symposium Series
Pages141-156
Number of pages16
Volume951
StatePublished - 2007

Publication series

NameACS Symposium Series
Volume951
ISSN (Print)00976156

Fingerprint

Pesticides
Labels
Atrazine
Immunosensors
Paraquat
Monitoring
Metabolites
Assays
Blood
Substitution reactions
Throughput
Nanoparticles
Fluids
Enzymes
Costs

ASJC Scopus subject areas

  • Chemistry(all)

Cite this

Koivunen, M. E., Gee, S. J., Nichkova, M., Ahn, K. C., & Hammock, B. D. (2007). Monitoring human exposure to pesticides using immunoassay. In ACS Symposium Series (Vol. 951, pp. 141-156). (ACS Symposium Series; Vol. 951).

Monitoring human exposure to pesticides using immunoassay. / Koivunen, Marja E.; Gee, Shirley J.; Nichkova, Mikaela; Ahn, Ki Chang; Hammock, Bruce D.

ACS Symposium Series. Vol. 951 2007. p. 141-156 (ACS Symposium Series; Vol. 951).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Koivunen, ME, Gee, SJ, Nichkova, M, Ahn, KC & Hammock, BD 2007, Monitoring human exposure to pesticides using immunoassay. in ACS Symposium Series. vol. 951, ACS Symposium Series, vol. 951, pp. 141-156.
Koivunen ME, Gee SJ, Nichkova M, Ahn KC, Hammock BD. Monitoring human exposure to pesticides using immunoassay. In ACS Symposium Series. Vol. 951. 2007. p. 141-156. (ACS Symposium Series).
Koivunen, Marja E. ; Gee, Shirley J. ; Nichkova, Mikaela ; Ahn, Ki Chang ; Hammock, Bruce D. / Monitoring human exposure to pesticides using immunoassay. ACS Symposium Series. Vol. 951 2007. pp. 141-156 (ACS Symposium Series).
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