Abstract
The crystal structure of the central region of Rad51 bound to a BRC peptide from BRCA2 shows that the BRC peptide mimics a structural motif within Rad51 and can thereby regulate assembly of the Rad51 nucleoprotein filament needed for DNA repair.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 897-899 |
| Number of pages | 3 |
| Journal | Nature Structural Biology |
| Volume | 9 |
| Issue number | 12 |
| DOIs | |
| State | Published - Dec 1 2002 |
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ASJC Scopus subject areas
- Biochemistry
- Structural Biology
- Genetics
Cite this
Molecular mimicry connects BRCA2 to Rad51 and recombinational DNA repair. / Kowalczykowski, Stephen C.
In: Nature Structural Biology, Vol. 9, No. 12, 01.12.2002, p. 897-899.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Molecular mimicry connects BRCA2 to Rad51 and recombinational DNA repair
AU - Kowalczykowski, Stephen C.
PY - 2002/12/1
Y1 - 2002/12/1
N2 - The crystal structure of the central region of Rad51 bound to a BRC peptide from BRCA2 shows that the BRC peptide mimics a structural motif within Rad51 and can thereby regulate assembly of the Rad51 nucleoprotein filament needed for DNA repair.
AB - The crystal structure of the central region of Rad51 bound to a BRC peptide from BRCA2 shows that the BRC peptide mimics a structural motif within Rad51 and can thereby regulate assembly of the Rad51 nucleoprotein filament needed for DNA repair.
UR - http://www.scopus.com/inward/record.url?scp=0036894879&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0036894879&partnerID=8YFLogxK
U2 - 10.1038/nsb1202-897
DO - 10.1038/nsb1202-897
M3 - Article
C2 - 12447354
AN - SCOPUS:0036894879
VL - 9
SP - 897
EP - 899
JO - Nature Structural and Molecular Biology
JF - Nature Structural and Molecular Biology
SN - 1545-9993
IS - 12
ER -