Abstract
The crystal structure of the central region of Rad51 bound to a BRC peptide from BRCA2 shows that the BRC peptide mimics a structural motif within Rad51 and can thereby regulate assembly of the Rad51 nucleoprotein filament needed for DNA repair.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 897-899 |
| Number of pages | 3 |
| Journal | Nature Structural Biology |
| Volume | 9 |
| Issue number | 12 |
| DOIs | |
| State | Published - Dec 1 2002 |
ASJC Scopus subject areas
- Biochemistry
- Structural Biology
- Genetics
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Cite this
Kowalczykowski, S. C. (2002). Molecular mimicry connects BRCA2 to Rad51 and recombinational DNA repair. Nature Structural Biology, 9(12), 897-899. https://doi.org/10.1038/nsb1202-897