Abstract
The crystal structure of the central region of Rad51 bound to a BRC peptide from BRCA2 shows that the BRC peptide mimics a structural motif within Rad51 and can thereby regulate assembly of the Rad51 nucleoprotein filament needed for DNA repair.
Original language | English (US) |
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Pages (from-to) | 897-899 |
Number of pages | 3 |
Journal | Nature Structural Biology |
Volume | 9 |
Issue number | 12 |
DOIs | |
State | Published - Dec 1 2002 |
ASJC Scopus subject areas
- Biochemistry
- Structural Biology
- Genetics