Molecular interactions in surface-assembled monolayers of short double-stranded DNA

Ling Huang, Erkin Seker, James P. Landers, Matthew R. Begley, Marcel Utz

Research output: Contribution to journalArticle

12 Scopus citations

Abstract

We present an experimental study of the energetics of repulsion between end-grafted fragments of double-stranded DNA. The absorption isotherm of thiolated DNA fragments has been measured as a function of DNA chain length as well as the salinity of the surrounding solution. The results are consistent with a simple excluded-volume model of the interaction between neighboring DNA strands.

Original languageEnglish (US)
Pages (from-to)11574-11580
Number of pages7
JournalLangmuir
Volume26
Issue number13
DOIs
StatePublished - Jul 6 2010
Externally publishedYes

ASJC Scopus subject areas

  • Materials Science(all)
  • Condensed Matter Physics
  • Surfaces and Interfaces
  • Spectroscopy
  • Electrochemistry

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