Molecular characterization of rheumatoid arthritis with magnetic resonance imaging

Jeffrey T. Gu, Linda Nguyen, Abhijit Chaudhari, John D. MacKenzie

Research output: Contribution to journalArticlepeer-review

6 Scopus citations

Abstract

Several recent advances in the field of magnetic resonance imaging (MRI) may transform the detection and monitoring of rheumatoid arthritis (RA). These advances depict both anatomic and molecular alterations from RA. Previous techniques could detect specific end products of metabolism in vitro or were limited to providing anatomic information. This review focuses on the novel molecular imaging techniques of hyperpolarized carbon-13 MRI, MRI with iron-labeled probes, and fusion of MRI with positron emission tomography. These new imaging approaches go beyond the anatomic description of RA and lend new information into the status of this disease by giving molecular information.

Original languageEnglish (US)
Pages (from-to)61-69
Number of pages9
JournalTopics in Magnetic Resonance Imaging
Volume22
Issue number2
DOIs
StatePublished - Apr 2011

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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