Molecular biology of autoantigens in rheumatic diseases

Research output: Contribution to journalArticle

3 Scopus citations

Abstract

The advent of molecular biologic techniques has provided new approaches that are of great utility to the study of autoimmune-mediated responses. In the past few years, there has been a remarkable accumulation of knowledge concerning the molecular identity and function of autoantigens, and further consolidation for the use of autoantibodies as diagnostic markers in clinical rheumatology. The understanding of basis methodologies in molecular biology applied to the study of autoantigens, in particular, techniques for cloning and analyzing genes that are important in rheumatic diseases, is valuable for both basic scientists and clinicians interested in diagnostic and prognostic markers of various connective tissue diseases.

Original languageEnglish (US)
Pages (from-to)175-210
Number of pages36
JournalRheumatic Disease Clinics of North America
Volume22
Issue number1
DOIs
StatePublished - 1996

ASJC Scopus subject areas

  • Rheumatology

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