Molecular Basis of Recovering on Mechanical Circulatory Support

Ali Nsair, David A. Liem, Martin Cadeiras, Richard K. Cheng, Mrudula Allareddy, Murray Kwon, Richard Shemin, Mario C. Deng

Research output: Contribution to journalReview article

2 Citations (Scopus)

Abstract

Our insights into different system levels of mechanisms by left ventricular assist device support are increasing and suggest a complex regulatory system of overlapping biological processes. To develop novel decision-making strategies and patient selection criteria, heart failure and reverse cardiac remodeling should be conceptualized and explored by a multifaceted research strategy of transcriptomics, metabolomics, proteomics, molecular biology, and bioinformatics. Knowledge of the molecular mechanisms of reverse cardiac remodeling is in its early stages, and comprehensive reconstruction of the underlying networks is necessary.

Original languageEnglish (US)
Pages (from-to)S57-S62
JournalHeart Failure Clinics
Volume10
Issue number1 SUPPL.
DOIs
StatePublished - Jan 1 2014
Externally publishedYes

Fingerprint

Patient Selection
Biological Phenomena
Heart-Assist Devices
Metabolomics
Computational Biology
Proteomics
Molecular Biology
Decision Making
Heart Failure
Research

Keywords

  • Advanced heart failure
  • Mechanical circulatory support
  • Molecular mechanisms
  • Reverse remodeling

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Nsair, A., Liem, D. A., Cadeiras, M., Cheng, R. K., Allareddy, M., Kwon, M., ... Deng, M. C. (2014). Molecular Basis of Recovering on Mechanical Circulatory Support. Heart Failure Clinics, 10(1 SUPPL.), S57-S62. https://doi.org/10.1016/j.hfc.2013.08.007

Molecular Basis of Recovering on Mechanical Circulatory Support. / Nsair, Ali; Liem, David A.; Cadeiras, Martin; Cheng, Richard K.; Allareddy, Mrudula; Kwon, Murray; Shemin, Richard; Deng, Mario C.

In: Heart Failure Clinics, Vol. 10, No. 1 SUPPL., 01.01.2014, p. S57-S62.

Research output: Contribution to journalReview article

Nsair, A, Liem, DA, Cadeiras, M, Cheng, RK, Allareddy, M, Kwon, M, Shemin, R & Deng, MC 2014, 'Molecular Basis of Recovering on Mechanical Circulatory Support', Heart Failure Clinics, vol. 10, no. 1 SUPPL., pp. S57-S62. https://doi.org/10.1016/j.hfc.2013.08.007
Nsair A, Liem DA, Cadeiras M, Cheng RK, Allareddy M, Kwon M et al. Molecular Basis of Recovering on Mechanical Circulatory Support. Heart Failure Clinics. 2014 Jan 1;10(1 SUPPL.):S57-S62. https://doi.org/10.1016/j.hfc.2013.08.007
Nsair, Ali ; Liem, David A. ; Cadeiras, Martin ; Cheng, Richard K. ; Allareddy, Mrudula ; Kwon, Murray ; Shemin, Richard ; Deng, Mario C. / Molecular Basis of Recovering on Mechanical Circulatory Support. In: Heart Failure Clinics. 2014 ; Vol. 10, No. 1 SUPPL. pp. S57-S62.
@article{8a3c79e7ee914b638d6723eebf2caed5,
title = "Molecular Basis of Recovering on Mechanical Circulatory Support",
abstract = "Our insights into different system levels of mechanisms by left ventricular assist device support are increasing and suggest a complex regulatory system of overlapping biological processes. To develop novel decision-making strategies and patient selection criteria, heart failure and reverse cardiac remodeling should be conceptualized and explored by a multifaceted research strategy of transcriptomics, metabolomics, proteomics, molecular biology, and bioinformatics. Knowledge of the molecular mechanisms of reverse cardiac remodeling is in its early stages, and comprehensive reconstruction of the underlying networks is necessary.",
keywords = "Advanced heart failure, Mechanical circulatory support, Molecular mechanisms, Reverse remodeling",
author = "Ali Nsair and Liem, {David A.} and Martin Cadeiras and Cheng, {Richard K.} and Mrudula Allareddy and Murray Kwon and Richard Shemin and Deng, {Mario C.}",
year = "2014",
month = "1",
day = "1",
doi = "10.1016/j.hfc.2013.08.007",
language = "English (US)",
volume = "10",
pages = "S57--S62",
journal = "Heart Failure Clinics",
issn = "1551-7136",
publisher = "Elsevier Inc.",
number = "1 SUPPL.",

}

TY - JOUR

T1 - Molecular Basis of Recovering on Mechanical Circulatory Support

AU - Nsair, Ali

AU - Liem, David A.

AU - Cadeiras, Martin

AU - Cheng, Richard K.

AU - Allareddy, Mrudula

AU - Kwon, Murray

AU - Shemin, Richard

AU - Deng, Mario C.

PY - 2014/1/1

Y1 - 2014/1/1

N2 - Our insights into different system levels of mechanisms by left ventricular assist device support are increasing and suggest a complex regulatory system of overlapping biological processes. To develop novel decision-making strategies and patient selection criteria, heart failure and reverse cardiac remodeling should be conceptualized and explored by a multifaceted research strategy of transcriptomics, metabolomics, proteomics, molecular biology, and bioinformatics. Knowledge of the molecular mechanisms of reverse cardiac remodeling is in its early stages, and comprehensive reconstruction of the underlying networks is necessary.

AB - Our insights into different system levels of mechanisms by left ventricular assist device support are increasing and suggest a complex regulatory system of overlapping biological processes. To develop novel decision-making strategies and patient selection criteria, heart failure and reverse cardiac remodeling should be conceptualized and explored by a multifaceted research strategy of transcriptomics, metabolomics, proteomics, molecular biology, and bioinformatics. Knowledge of the molecular mechanisms of reverse cardiac remodeling is in its early stages, and comprehensive reconstruction of the underlying networks is necessary.

KW - Advanced heart failure

KW - Mechanical circulatory support

KW - Molecular mechanisms

KW - Reverse remodeling

UR - http://www.scopus.com/inward/record.url?scp=84888033825&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84888033825&partnerID=8YFLogxK

U2 - 10.1016/j.hfc.2013.08.007

DO - 10.1016/j.hfc.2013.08.007

M3 - Review article

C2 - 24262353

AN - SCOPUS:84888033825

VL - 10

SP - S57-S62

JO - Heart Failure Clinics

JF - Heart Failure Clinics

SN - 1551-7136

IS - 1 SUPPL.

ER -