Molecular basis of gene-for-gene specificity in bacterial speck disease of tomato

Steven R. Scofield, Christian M. Tobias, John P. Rathjen, Jeff H. Chang, Daniel T. Lavelle, Richard W Michelmore, Brian J. Staskawicz

Research output: Contribution to journalArticlepeer-review

421 Scopus citations

Abstract

Transient expression of the Pseudomonas syringae avirulence gene avrPto in plant cells resulted in a Pto-dependent necrosis. The AvrPto avirulence protein was observed to interact directly with the Pto resistance protein in the yeast two-hybrid system. Mutations in the Pto and avrPto genes which reduce in vivo activity had parallel effects on association in the two- hybrid assay. These data suggest that during infection the pathogen delivers AvrPto into the plant host cell and that resistance is specified by direct interaction of Pto with AvrPto.

Original languageEnglish (US)
Pages (from-to)2063-2065
Number of pages3
JournalScience
Volume274
Issue number5295
DOIs
StatePublished - Dec 20 1996

ASJC Scopus subject areas

  • General

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