Abstract
Microtubule dynamics change dramatically during the cell cycle, but the mechanisms by which these changes occur are unknown. Recent progress has been made in four areas: firstly, in the determination of changes in microtubule turnover and net tubulin polymer levels in vivo; secondly, in the elucidation of mechanisms of regulation of microtubule dynamics by microtubule-associated protein 4; thirdly, in the determination of the mechanisms by which Xenopus microtubule-associated protein regulates microtubule dynamics; and fourthly, in the elucidation of the structural basis of microtubule nucleation by γ tubulin.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 23-29 |
| Number of pages | 7 |
| Journal | Current Opinion in Cell Biology |
| Volume | 8 |
| Issue number | 1 |
| DOIs | |
| State | Published - Feb 1996 |
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ASJC Scopus subject areas
- Cell Biology
Cite this
Modulation of microtubule dynamics during the cell cycle. / McNally, Francis J.
In: Current Opinion in Cell Biology, Vol. 8, No. 1, 02.1996, p. 23-29.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Modulation of microtubule dynamics during the cell cycle
AU - McNally, Francis J.
PY - 1996/2
Y1 - 1996/2
N2 - Microtubule dynamics change dramatically during the cell cycle, but the mechanisms by which these changes occur are unknown. Recent progress has been made in four areas: firstly, in the determination of changes in microtubule turnover and net tubulin polymer levels in vivo; secondly, in the elucidation of mechanisms of regulation of microtubule dynamics by microtubule-associated protein 4; thirdly, in the determination of the mechanisms by which Xenopus microtubule-associated protein regulates microtubule dynamics; and fourthly, in the elucidation of the structural basis of microtubule nucleation by γ tubulin.
AB - Microtubule dynamics change dramatically during the cell cycle, but the mechanisms by which these changes occur are unknown. Recent progress has been made in four areas: firstly, in the determination of changes in microtubule turnover and net tubulin polymer levels in vivo; secondly, in the elucidation of mechanisms of regulation of microtubule dynamics by microtubule-associated protein 4; thirdly, in the determination of the mechanisms by which Xenopus microtubule-associated protein regulates microtubule dynamics; and fourthly, in the elucidation of the structural basis of microtubule nucleation by γ tubulin.
UR - http://www.scopus.com/inward/record.url?scp=0030060174&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0030060174&partnerID=8YFLogxK
U2 - 10.1016/S0955-0674(96)80044-5
DO - 10.1016/S0955-0674(96)80044-5
M3 - Article
VL - 8
SP - 23
EP - 29
JO - Current Opinion in Cell Biology
JF - Current Opinion in Cell Biology
SN - 0955-0674
IS - 1
ER -