Mitotic Motors: Kinesin-5 Takes a Brake

Gul Civelekoglu-Scholey; Jonathan M. Scholey

doi:10.1016/j.cub.2007.05.030

Mitotic Motors: Kinesin-5 Takes a Brake

Gul Civelekoglu-Scholey, Jonathan M. Scholey

Molecular and Cellular Biology

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Abstract

A kinesin-5-dependent 'sliding filament' mechanism is commonly used to actively push apart the poles during mitotic spindle assembly and elongation, but a recent study now shows that, in C. elegans, kinesin-5 is deployed as a brake to slow down spindle-pole separation.

Original language	English (US)
Journal	Current Biology
Volume	17
Issue number	14
DOIs	https://doi.org/10.1016/j.cub.2007.05.030
State	Published - Jul 17 2007

ASJC Scopus subject areas

Agricultural and Biological Sciences(all)

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title = "Mitotic Motors: Kinesin-5 Takes a Brake",

abstract = "A kinesin-5-dependent 'sliding filament' mechanism is commonly used to actively push apart the poles during mitotic spindle assembly and elongation, but a recent study now shows that, in C. elegans, kinesin-5 is deployed as a brake to slow down spindle-pole separation.",

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