Minoxidil in refractory hypertension

Sudesh P Makker

doi:10.1016/S0022-3476(75)80167-3

Minoxidil in refractory hypertension

Sudesh P Makker

Research output: Contribution to journal › Article › peer-review

13 Scopus citations

Abstract

A life-threatening, severe, hypertension refractory to conventional antihypertensive drugs developed in a 10-year-old girl in association with a functional renal transplant. Minoxidil, a new vasodilator, proved to be a lifesaving antihypertensive drug and prevented the removal of the functional transplant. During 9 months of minoxidil therapy the blood pressure remained controlled and the renal transplant function excellent. No serious side effects except a moderate hypertrichosis have been observed. It appears that minoxidil can be used to control refractory, life-theratening hypertension in children.

Original language	English (US)
Pages (from-to)	621-623
Number of pages	3
Journal	The Journal of Pediatrics
Volume	86
Issue number	4
DOIs	https://doi.org/10.1016/S0022-3476(75)80167-3
State	Published - 1975
Externally published	Yes

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health

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abstract = "A life-threatening, severe, hypertension refractory to conventional antihypertensive drugs developed in a 10-year-old girl in association with a functional renal transplant. Minoxidil, a new vasodilator, proved to be a lifesaving antihypertensive drug and prevented the removal of the functional transplant. During 9 months of minoxidil therapy the blood pressure remained controlled and the renal transplant function excellent. No serious side effects except a moderate hypertrichosis have been observed. It appears that minoxidil can be used to control refractory, life-theratening hypertension in children.",

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AB - A life-threatening, severe, hypertension refractory to conventional antihypertensive drugs developed in a 10-year-old girl in association with a functional renal transplant. Minoxidil, a new vasodilator, proved to be a lifesaving antihypertensive drug and prevented the removal of the functional transplant. During 9 months of minoxidil therapy the blood pressure remained controlled and the renal transplant function excellent. No serious side effects except a moderate hypertrichosis have been observed. It appears that minoxidil can be used to control refractory, life-theratening hypertension in children.

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