Minimally invasive therapies for chronic pelvic pain syndrome

Salim A. Wehbe, Jennifer Y. Fariello, Kristene Whitmore

Research output: Contribution to journalArticlepeer-review

15 Scopus citations


Chronic pelvic pain syndrome (CPPS) is a common problem among men and women worldwide. It is a symptoms-complex term for interstitial cystitis/painful bladder syndrome in women and chronic prostatitis/chronic pelvic pain syndrome in men. Patients often present with a combination of lower urinary tract symptoms with pelvic pain and sexual dysfunction. No gold standard exists for diagnosis or treatment of CPPS. The diagnosis is often challenging and is determined by elimination. Multiple treatment modalities exist, ranging from physical therapy to surgery. We discuss minimally invasive therapies for treatment of this complex of symptoms. Although data suggest reasonable efficacy of several medications, multimodal therapy remains the mainstay of treatment. We review the following minimally invasive therapeutic modalities: dietary modifications, physical therapy, mind-body therapies, medical therapy, intravesical therapies, trigger point injections, botulinum toxin injections to the pelvic floor, and neuromodulation. We report data supporting their use and efficacy and highlight the limitations of each.

Original languageEnglish (US)
Pages (from-to)276-285
Number of pages10
JournalCurrent Urology Reports
Issue number4
StatePublished - Jul 2010
Externally publishedYes


  • Chronic pelvic pain syndrome
  • Chronic prostatitis
  • Interstitial cystitis
  • Minimally invasive therapy

ASJC Scopus subject areas

  • Urology
  • Medicine(all)


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