Miniaturized side-viewing imaging probe for fluorescence lifetime imaging (FLIM)

Validation with fluorescence dyes, tissue structural proteins and tissue specimens

D. S. Elson, J. A. Jo, Laura Marcu

Research output: Contribution to journalArticle

36 Citations (Scopus)

Abstract

We report a side viewing fibre-based endoscope that is compatible with intravascular imaging and fluorescence lifetime imaging microscopy (FLIM). The instrument has been validated through testing with fluorescent dyes and collagen and elastin powders using the Laguerre expansion deconvolution technique to calculate the fluorescence lifetimes. The instrument has also been tested on freshly excised unstained animal vascular tissues.

Original languageEnglish (US)
Article number127
JournalNew Journal of Physics
Volume9
DOIs
StatePublished - May 17 2007

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dyes
elastin
proteins
life (durability)
endoscopes
fluorescence
probes
collagens
animals
microscopy
expansion
fibers

ASJC Scopus subject areas

  • Physics and Astronomy(all)

Cite this

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abstract = "We report a side viewing fibre-based endoscope that is compatible with intravascular imaging and fluorescence lifetime imaging microscopy (FLIM). The instrument has been validated through testing with fluorescent dyes and collagen and elastin powders using the Laguerre expansion deconvolution technique to calculate the fluorescence lifetimes. The instrument has also been tested on freshly excised unstained animal vascular tissues.",
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