Miniature differential mobility spectrometry (DMS) advances towards portable autonomous health diagnostic systems

Weixiang Zhao, Abhinav Bhushan, Michael Schivo, Nicholas Kenyon, Cristina E Davis

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations

Abstract

Many modern analytical instruments, such as mass spectrometry, have been developed to provide insight into the biochemical content of many different biological sample types. Typically these instruments are large bench-top machines that have very high sensitivity and specificity for the compounds they detect. However, these instruments are not mobile or autonomous, and they require highly trained personnel to operate. There have been many developments in the area of miniature chemical sensors that can maintain performance levels observed in large traditional bio-analytical instruments, but are low-power and potentially mobile and autonomous in function. Miniature differential mobility spectrometry (DMS) is a small instrument that can potentially be used in point-of-care diagnostic applications. This chapter will review the significant advances in this emerging research area, and provide insight as to how these systems could be further improved and adapted for use in autonomous health monitoring and sensing systems.

Original languageEnglish (US)
Title of host publicationLecture Notes in Electrical Engineering
Pages55-73
Number of pages19
Volume75 LNEE
DOIs
StatePublished - 2010

Publication series

NameLecture Notes in Electrical Engineering
Volume75 LNEE
ISSN (Print)18761100
ISSN (Electronic)18761119

Keywords

  • breath analysis
  • chemometrics
  • differential mobility spectrometry (DMS)
  • non-invasive disease diagnostics

ASJC Scopus subject areas

  • Industrial and Manufacturing Engineering

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  • Cite this

    Zhao, W., Bhushan, A., Schivo, M., Kenyon, N., & Davis, C. E. (2010). Miniature differential mobility spectrometry (DMS) advances towards portable autonomous health diagnostic systems. In Lecture Notes in Electrical Engineering (Vol. 75 LNEE, pp. 55-73). (Lecture Notes in Electrical Engineering; Vol. 75 LNEE). https://doi.org/10.1007/978-3-642-15687-8-3