Abstract
Many modern analytical instruments, such as mass spectrometry, have been developed to provide insight into the biochemical content of many different biological sample types. Typically these instruments are large bench-top machines that have very high sensitivity and specificity for the compounds they detect. However, these instruments are not mobile or autonomous, and they require highly trained personnel to operate. There have been many developments in the area of miniature chemical sensors that can maintain performance levels observed in large traditional bio-analytical instruments, but are low-power and potentially mobile and autonomous in function. Miniature differential mobility spectrometry (DMS) is a small instrument that can potentially be used in point-of-care diagnostic applications. This chapter will review the significant advances in this emerging research area, and provide insight as to how these systems could be further improved and adapted for use in autonomous health monitoring and sensing systems.
| Original language | English (US) |
|---|---|
| Title of host publication | Lecture Notes in Electrical Engineering |
| Pages | 55-73 |
| Number of pages | 19 |
| Volume | 75 LNEE |
| DOIs | |
| State | Published - 2010 |
Publication series
| Name | Lecture Notes in Electrical Engineering |
|---|---|
| Volume | 75 LNEE |
| ISSN (Print) | 18761100 |
| ISSN (Electronic) | 18761119 |
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Keywords
- breath analysis
- chemometrics
- differential mobility spectrometry (DMS)
- non-invasive disease diagnostics
ASJC Scopus subject areas
- Industrial and Manufacturing Engineering
Cite this
Miniature differential mobility spectrometry (DMS) advances towards portable autonomous health diagnostic systems. / Zhao, Weixiang; Bhushan, Abhinav; Schivo, Michael; Kenyon, Nicholas; Davis, Cristina E.
Lecture Notes in Electrical Engineering. Vol. 75 LNEE 2010. p. 55-73 (Lecture Notes in Electrical Engineering; Vol. 75 LNEE).Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
}
TY - GEN
T1 - Miniature differential mobility spectrometry (DMS) advances towards portable autonomous health diagnostic systems
AU - Zhao, Weixiang
AU - Bhushan, Abhinav
AU - Schivo, Michael
AU - Kenyon, Nicholas
AU - Davis, Cristina E
PY - 2010
Y1 - 2010
N2 - Many modern analytical instruments, such as mass spectrometry, have been developed to provide insight into the biochemical content of many different biological sample types. Typically these instruments are large bench-top machines that have very high sensitivity and specificity for the compounds they detect. However, these instruments are not mobile or autonomous, and they require highly trained personnel to operate. There have been many developments in the area of miniature chemical sensors that can maintain performance levels observed in large traditional bio-analytical instruments, but are low-power and potentially mobile and autonomous in function. Miniature differential mobility spectrometry (DMS) is a small instrument that can potentially be used in point-of-care diagnostic applications. This chapter will review the significant advances in this emerging research area, and provide insight as to how these systems could be further improved and adapted for use in autonomous health monitoring and sensing systems.
AB - Many modern analytical instruments, such as mass spectrometry, have been developed to provide insight into the biochemical content of many different biological sample types. Typically these instruments are large bench-top machines that have very high sensitivity and specificity for the compounds they detect. However, these instruments are not mobile or autonomous, and they require highly trained personnel to operate. There have been many developments in the area of miniature chemical sensors that can maintain performance levels observed in large traditional bio-analytical instruments, but are low-power and potentially mobile and autonomous in function. Miniature differential mobility spectrometry (DMS) is a small instrument that can potentially be used in point-of-care diagnostic applications. This chapter will review the significant advances in this emerging research area, and provide insight as to how these systems could be further improved and adapted for use in autonomous health monitoring and sensing systems.
KW - breath analysis
KW - chemometrics
KW - differential mobility spectrometry (DMS)
KW - non-invasive disease diagnostics
UR - http://www.scopus.com/inward/record.url?scp=78651593629&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=78651593629&partnerID=8YFLogxK
U2 - 10.1007/978-3-642-15687-8-3
DO - 10.1007/978-3-642-15687-8-3
M3 - Conference contribution
AN - SCOPUS:78651593629
SN - 9783642156861
VL - 75 LNEE
T3 - Lecture Notes in Electrical Engineering
SP - 55
EP - 73
BT - Lecture Notes in Electrical Engineering
ER -