Milk amyloid A (MAA) concentration and somatic cell count (SCC) in the diagnosis of bovine mastitis

H. H. Petersen, Ian Gardner, P. Rossitto, H. D. Larsen, P. M H Heegaard

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations


One-hundred-thirty-one dairy cows from 5 herds in the Central Valley of California were selected based on somatic cell count and mastitis records, days in milk in the current lactation and lactation group to ensure an adequate spectrum of cases. All cows were clinically examined and milk samples were obtained from 2 contra-lateral quarters. From cows with clinical signs of mastitis, the affected and the contra-lateral quarter were sampled. The milk was submitted for microbiology, somatic cell count (SCC) and milk amyloid A (MAA) testing. If clinical signs were present or culturing revealed mastitis agents, the quarter was classified as mastitic. If no clinical signs were present and the culture was negative, the quarter was classified as healthy. If multiple cultures were present, the sample was classified as contaminated. We found that the SCC and MAA-concentration were not correlated (n=254, R2 = 0.08). ROC-curves demonstrated an area under the curve (AUC) of 0.80 for MAA and 0.77 for SCC (n=230). These areas were not statistically different. This indicates that despite no overall difference in diagnostic performance, the SCC and MAA may have different diagnostic potentials that could depend on factors such as causative agents or degree of tissue damage.

Original languageEnglish (US)
Title of host publicationMastitis in Dairy Production
Subtitle of host publicationCurrent Knowledge and Future Solutions
PublisherWageningen Academic Publishers
Number of pages4
ISBN (Print)9789076998701
StatePublished - Dec 1 2005


  • Diagnostic performance
  • Milk amyloid A
  • Somatic cell count

ASJC Scopus subject areas

  • Agricultural and Biological Sciences(all)
  • Engineering(all)


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