Migrating motility complexes persist after severe traumatic shock in patients who tolerate enteral nutrition

F. A. Moore, Christine S Cocanour, B. A. McKinley, R. A. Kozar, R. C. DeSoignie, M. E. Von-Maszewski, N. W. Weisbrodt

Research output: Contribution to journalArticle

34 Citations (Scopus)

Abstract

Background: Postinjury small bowel ileus is poorly characterized and may be an important factor in intolerance to enteral nutrition (EN). We, therefore, placed jejunal manometry catheters in high-risk trauma patients. Our hypothesis was that the presence of "fasting migrating motility complex (MMC)" activity and conversion to a "fed pattern" at goal rate of EN would be present in those patients who tolerate jejunal feeding. Methods: After obtaining baseline fasting manometry pressure tracings, jejunal feeding was advanced stepwise to a set goal while tolerance was monitored and intolerance was treated by a standard approach. Results: Of the 10 study patients, 7 were able to be maintained on EN. Five (50%) had "fasting MMCs" and had good tolerance to early advancement of EN. The remaining five patients did not exhibit "fasting MMCs" and four had poor tolerance to early advancement of EN. Overall, nine patients reached goal rate of EN of which four converted to a "fed pattern." This, however, was not associated with later tolerance to EN. Conclusion: EN is feasible following severe traumatic shock. Surprisingly, half of the patients had fasting MMCs. This requires intact neural and motor function and was associated with good tolerance of early EN.

Original languageEnglish (US)
Pages (from-to)1075-1082
Number of pages8
JournalJournal of Trauma - Injury, Infection and Critical Care
Volume51
Issue number6
StatePublished - 2001
Externally publishedYes

Fingerprint

Traumatic Shock
Enteral Nutrition
Fasting
Manometry
Ileus
Catheters
Pressure

ASJC Scopus subject areas

  • Surgery

Cite this

Moore, F. A., Cocanour, C. S., McKinley, B. A., Kozar, R. A., DeSoignie, R. C., Von-Maszewski, M. E., & Weisbrodt, N. W. (2001). Migrating motility complexes persist after severe traumatic shock in patients who tolerate enteral nutrition. Journal of Trauma - Injury, Infection and Critical Care, 51(6), 1075-1082.

Migrating motility complexes persist after severe traumatic shock in patients who tolerate enteral nutrition. / Moore, F. A.; Cocanour, Christine S; McKinley, B. A.; Kozar, R. A.; DeSoignie, R. C.; Von-Maszewski, M. E.; Weisbrodt, N. W.

In: Journal of Trauma - Injury, Infection and Critical Care, Vol. 51, No. 6, 2001, p. 1075-1082.

Research output: Contribution to journalArticle

Moore, FA, Cocanour, CS, McKinley, BA, Kozar, RA, DeSoignie, RC, Von-Maszewski, ME & Weisbrodt, NW 2001, 'Migrating motility complexes persist after severe traumatic shock in patients who tolerate enteral nutrition', Journal of Trauma - Injury, Infection and Critical Care, vol. 51, no. 6, pp. 1075-1082.
Moore, F. A. ; Cocanour, Christine S ; McKinley, B. A. ; Kozar, R. A. ; DeSoignie, R. C. ; Von-Maszewski, M. E. ; Weisbrodt, N. W. / Migrating motility complexes persist after severe traumatic shock in patients who tolerate enteral nutrition. In: Journal of Trauma - Injury, Infection and Critical Care. 2001 ; Vol. 51, No. 6. pp. 1075-1082.
@article{36cc06b8f71847d6a1a7fe4619585254,
title = "Migrating motility complexes persist after severe traumatic shock in patients who tolerate enteral nutrition",
abstract = "Background: Postinjury small bowel ileus is poorly characterized and may be an important factor in intolerance to enteral nutrition (EN). We, therefore, placed jejunal manometry catheters in high-risk trauma patients. Our hypothesis was that the presence of {"}fasting migrating motility complex (MMC){"} activity and conversion to a {"}fed pattern{"} at goal rate of EN would be present in those patients who tolerate jejunal feeding. Methods: After obtaining baseline fasting manometry pressure tracings, jejunal feeding was advanced stepwise to a set goal while tolerance was monitored and intolerance was treated by a standard approach. Results: Of the 10 study patients, 7 were able to be maintained on EN. Five (50{\%}) had {"}fasting MMCs{"} and had good tolerance to early advancement of EN. The remaining five patients did not exhibit {"}fasting MMCs{"} and four had poor tolerance to early advancement of EN. Overall, nine patients reached goal rate of EN of which four converted to a {"}fed pattern.{"} This, however, was not associated with later tolerance to EN. Conclusion: EN is feasible following severe traumatic shock. Surprisingly, half of the patients had fasting MMCs. This requires intact neural and motor function and was associated with good tolerance of early EN.",
author = "Moore, {F. A.} and Cocanour, {Christine S} and McKinley, {B. A.} and Kozar, {R. A.} and DeSoignie, {R. C.} and Von-Maszewski, {M. E.} and Weisbrodt, {N. W.}",
year = "2001",
language = "English (US)",
volume = "51",
pages = "1075--1082",
journal = "Journal of Trauma and Acute Care Surgery",
issn = "2163-0755",
publisher = "Lippincott Williams and Wilkins",
number = "6",

}

TY - JOUR

T1 - Migrating motility complexes persist after severe traumatic shock in patients who tolerate enteral nutrition

AU - Moore, F. A.

AU - Cocanour, Christine S

AU - McKinley, B. A.

AU - Kozar, R. A.

AU - DeSoignie, R. C.

AU - Von-Maszewski, M. E.

AU - Weisbrodt, N. W.

PY - 2001

Y1 - 2001

N2 - Background: Postinjury small bowel ileus is poorly characterized and may be an important factor in intolerance to enteral nutrition (EN). We, therefore, placed jejunal manometry catheters in high-risk trauma patients. Our hypothesis was that the presence of "fasting migrating motility complex (MMC)" activity and conversion to a "fed pattern" at goal rate of EN would be present in those patients who tolerate jejunal feeding. Methods: After obtaining baseline fasting manometry pressure tracings, jejunal feeding was advanced stepwise to a set goal while tolerance was monitored and intolerance was treated by a standard approach. Results: Of the 10 study patients, 7 were able to be maintained on EN. Five (50%) had "fasting MMCs" and had good tolerance to early advancement of EN. The remaining five patients did not exhibit "fasting MMCs" and four had poor tolerance to early advancement of EN. Overall, nine patients reached goal rate of EN of which four converted to a "fed pattern." This, however, was not associated with later tolerance to EN. Conclusion: EN is feasible following severe traumatic shock. Surprisingly, half of the patients had fasting MMCs. This requires intact neural and motor function and was associated with good tolerance of early EN.

AB - Background: Postinjury small bowel ileus is poorly characterized and may be an important factor in intolerance to enteral nutrition (EN). We, therefore, placed jejunal manometry catheters in high-risk trauma patients. Our hypothesis was that the presence of "fasting migrating motility complex (MMC)" activity and conversion to a "fed pattern" at goal rate of EN would be present in those patients who tolerate jejunal feeding. Methods: After obtaining baseline fasting manometry pressure tracings, jejunal feeding was advanced stepwise to a set goal while tolerance was monitored and intolerance was treated by a standard approach. Results: Of the 10 study patients, 7 were able to be maintained on EN. Five (50%) had "fasting MMCs" and had good tolerance to early advancement of EN. The remaining five patients did not exhibit "fasting MMCs" and four had poor tolerance to early advancement of EN. Overall, nine patients reached goal rate of EN of which four converted to a "fed pattern." This, however, was not associated with later tolerance to EN. Conclusion: EN is feasible following severe traumatic shock. Surprisingly, half of the patients had fasting MMCs. This requires intact neural and motor function and was associated with good tolerance of early EN.

UR - http://www.scopus.com/inward/record.url?scp=0035672673&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0035672673&partnerID=8YFLogxK

M3 - Article

C2 - 11740256

AN - SCOPUS:0035672673

VL - 51

SP - 1075

EP - 1082

JO - Journal of Trauma and Acute Care Surgery

JF - Journal of Trauma and Acute Care Surgery

SN - 2163-0755

IS - 6

ER -