Mid-term outcomes of orbital atherectomy combined with drug-coated balloon angioplasty for treatment of femoropopliteal disease

T. Raymond Foley, Ryan P. Cotter, Damianos G. Kokkinidis, Daniel D. Nguyen, Stephen W. Waldo, Ehrin J. Armstrong

Research output: Contribution to journalArticle

25 Scopus citations

Abstract

Purpose: To assess the intraprocedural and mid-term outcomes of orbital atherectomy (OA) combined with drug-coated balloon (DCB) angioplasty for the treatment of calcified femoropopliteal disease. Methods: In this single-center cohort, 89 patients (139 lesions) were treated with DCB angioplasty for claudication or critical limb ischemia (CLI). Angiographic characteristics and procedural outcomes were reviewed for patients treated with or without adjunctive OA. Lesion calcification was graded using two previously published scoring systems, the angiographic calcium score (ACS) and the peripheral artery calcification scoring system (PACSS). Results: Among 139 lesions, 40 (29%) were treated with OA+DCB. Mean lesion length was 135±100 mm for lesions treated with OA+DCB and 139±100 mm for DCB alone (P=0.9). Moderate to severe calcification was present in 83% of patients treated with OA, compared to 42% of patients treated with DCB alone (P<0.001). Lesions treated with OA+DCB were less likely to require bailout stenting (18% vs. 39%, P =0.01). Rates of embolization (0% in OA+DCB vs. 2% in DCB only, P=0.4), dissection (13% vs. 14%, P=0.8), and perforation (0%) did not differ significantly between groups. The freedom from TLR at 1 year was 82% in both groups (P=0.6) while primary patency was 81% in-patients treated with DCB alone and 77% in-patients treated with DCB with concomitant OA (P=0.8). Conclusion: In this single-center analysis of patients undergoing DCB angioplasty for claudication or CLI, OA was most often used for the treatment of severely calcified lesions. These lesions were more likely to be treated with scoring balloons and less likely to require bailout stenting. At 1 year, target lesion revascularization and primary patency was similar in patients treated with and without adjunctive OA, despite the higher lesion complexity among those receiving the combination procedure.

Original languageEnglish (US)
JournalCatheterization and Cardiovascular Interventions
DOIs
StateAccepted/In press - 2017
Externally publishedYes

Keywords

  • Calcification
  • Peripheral artery disease
  • Peripheral intervention
  • Superficial femoral artery

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine

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