Abstract
The surface modification of various nanoparticles with silica has been exploited to increase their utility for bioapplications. However, silica encapsulation through conventional methods requires long reaction times (hours to days). Herein, we demonstrated that uniform and spherical silica encapsulation of magnetic nanoparticles can be achieved within 10 min via microwave irradiation after phase transferring monodisperse magnetic nanoparticles from organic to water phase. In addition, we showed that silica shell addition through microwave synthesis is more effective than conventional heating methods, such as a hot plate. The approach that we propose may be useful in preparing multifunctional nano-probes, particularly for radiolabeling, which requires fast preparation times.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 8449-8454 |
| Number of pages | 6 |
| Journal | Journal of Materials Chemistry |
| Volume | 22 |
| Issue number | 17 |
| DOIs | |
| State | Published - May 7 2012 |
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ASJC Scopus subject areas
- Materials Chemistry
- Chemistry(all)
Cite this
Microwave enhanced silica encapsulation of magnetic nanoparticles. / Park, Jeong Chan; Gilbert, Dustin A.; Liu, Kai; Louie, Angelique Y.
In: Journal of Materials Chemistry, Vol. 22, No. 17, 07.05.2012, p. 8449-8454.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Microwave enhanced silica encapsulation of magnetic nanoparticles
AU - Park, Jeong Chan
AU - Gilbert, Dustin A.
AU - Liu, Kai
AU - Louie, Angelique Y.
PY - 2012/5/7
Y1 - 2012/5/7
N2 - The surface modification of various nanoparticles with silica has been exploited to increase their utility for bioapplications. However, silica encapsulation through conventional methods requires long reaction times (hours to days). Herein, we demonstrated that uniform and spherical silica encapsulation of magnetic nanoparticles can be achieved within 10 min via microwave irradiation after phase transferring monodisperse magnetic nanoparticles from organic to water phase. In addition, we showed that silica shell addition through microwave synthesis is more effective than conventional heating methods, such as a hot plate. The approach that we propose may be useful in preparing multifunctional nano-probes, particularly for radiolabeling, which requires fast preparation times.
AB - The surface modification of various nanoparticles with silica has been exploited to increase their utility for bioapplications. However, silica encapsulation through conventional methods requires long reaction times (hours to days). Herein, we demonstrated that uniform and spherical silica encapsulation of magnetic nanoparticles can be achieved within 10 min via microwave irradiation after phase transferring monodisperse magnetic nanoparticles from organic to water phase. In addition, we showed that silica shell addition through microwave synthesis is more effective than conventional heating methods, such as a hot plate. The approach that we propose may be useful in preparing multifunctional nano-probes, particularly for radiolabeling, which requires fast preparation times.
UR - http://www.scopus.com/inward/record.url?scp=84859738244&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84859738244&partnerID=8YFLogxK
U2 - 10.1039/c2jm16595c
DO - 10.1039/c2jm16595c
M3 - Article
VL - 22
SP - 8449
EP - 8454
JO - Journal of Materials Chemistry
JF - Journal of Materials Chemistry
SN - 0959-9428
IS - 17
ER -