Abstract
A variety of N-aryl β-nitroenamines were effectively transformed into 3-nitroindoles in good yields and with complete regioselectivity via a rapid microwave (μW) assisted intramolecular arene-alkene coupling reaction. This report further demonstrates the versatility of this method by constructing 3-carboalkoxy-and 3-cyanoindoles. Optimization data, substrate scope, and applications are discussed.
Original language | English (US) |
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Pages (from-to) | 362-365 |
Number of pages | 4 |
Journal | Organic Letters |
Volume | 15 |
Issue number | 2 |
DOIs | |
State | Published - Jan 18 2013 |
ASJC Scopus subject areas
- Organic Chemistry
- Physical and Theoretical Chemistry
- Biochemistry