Microsomal and cytosolic epoxide hydrolases in rhesus monkey liver, and in normal and neoplastic human liver

Sarjeet S. Gill, Kenji Ota, Boris Ruebner, Bruce D. Hammock

Research output: Contribution to journalArticle

31 Scopus citations

Abstract

The cytosolic epoxide hydrolase (EH-LC) was observed in rhesus monkey liver cytosol, and in both normal and neoplastic human liver. Microsomal epoxide hydrolase (EH-LM) was detected not only in the microsomes of normal and neoplastic human liver and normal rhesus monkey liver, but also in the cytosol of these tissues. No apparent differences were observed between the EH-LM in liver cytosol and that in microsomes. No major differences were observed between the levels of EH-LM in the cytosol of normal and that in neoplastic human liver.

Original languageEnglish (US)
Pages (from-to)2693-2700
Number of pages8
JournalLife Sciences
Volume32
Issue number23
DOIs
StatePublished - Jun 6 1983

ASJC Scopus subject areas

  • Pharmacology

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