Micronutrient antioxidants and smoking

Carroll E Cross, Maret Traber, Jason Eiserich, Albert Van Der Vliet

Research output: Contribution to journalArticle

54 Citations (Scopus)

Abstract

Cigarette smoking is a major risk factor in such human diseases as cardiovascular disease (especially atherosclerosis), lung cancer (the leading world-wide cancer killer), and chronic obstructive pulmonary disease (COPD). An avalanche of studies has suggested that a diet rich in fruit and vegetables is associated with decreased risk for atherosclerosis and cancer. However, the dietary intake of fruits and vegetables, as well as antioxidant micronutrients, is decreased in smokers. This, along with evidence of increased utilization of ascorbic acid and α-tocopherol, possibly on the basis of increased oxidative stress, contributes to the low plasma antioxidant concentrations seen in many smokers. This review addresses selected mechanistic considerations of this relationship.

Original languageEnglish (US)
Pages (from-to)691-704
Number of pages14
JournalBritish Medical Bulletin
Volume55
Issue number3
StatePublished - 1999

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Micronutrients
Vegetables
Fruit
Atherosclerosis
Antioxidants
Smoking
Avalanches
Tocopherols
Chronic Obstructive Pulmonary Disease
Ascorbic Acid
Lung Neoplasms
Neoplasms
Oxidative Stress
Cardiovascular Diseases
Diet

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Cross, C. E., Traber, M., Eiserich, J., & Van Der Vliet, A. (1999). Micronutrient antioxidants and smoking. British Medical Bulletin, 55(3), 691-704.

Micronutrient antioxidants and smoking. / Cross, Carroll E; Traber, Maret; Eiserich, Jason; Van Der Vliet, Albert.

In: British Medical Bulletin, Vol. 55, No. 3, 1999, p. 691-704.

Research output: Contribution to journalArticle

Cross, CE, Traber, M, Eiserich, J & Van Der Vliet, A 1999, 'Micronutrient antioxidants and smoking', British Medical Bulletin, vol. 55, no. 3, pp. 691-704.
Cross CE, Traber M, Eiserich J, Van Der Vliet A. Micronutrient antioxidants and smoking. British Medical Bulletin. 1999;55(3):691-704.
Cross, Carroll E ; Traber, Maret ; Eiserich, Jason ; Van Der Vliet, Albert. / Micronutrient antioxidants and smoking. In: British Medical Bulletin. 1999 ; Vol. 55, No. 3. pp. 691-704.
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