Microfluidic sample preparation for immunoassays

Steven Visuri; William Benett; Kerry Bettencourt; John T Chang; Karl Fisher; Julie Hamilton; Peter Krulevitch; Christina Park; Cheryl Stockton; Lisa Tarte; Amy Wang; Thomas Wilson

doi:10.1117/12.443043

Microfluidic sample preparation for immunoassays

Steven Visuri, William Benett, Kerry Bettencourt, John T Chang, Karl Fisher, Julie Hamilton, Peter Krulevitch, Christina Park, Cheryl Stockton, Lisa Tarte, Amy Wang, Thomas Wilson

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

4 Scopus citations

Abstract

Researchers at Lawrence Livermore National Laboratory are developing means to collect and identify fluid-based biological pathogens in the forms of proteins, viruses, and bacteria. To support detection instruments, we are developing a flexible fluidic sample preparation unit. The overall goal of this Microfluidic Module is to input a fluid sample, containing background particulates and potentially target compounds, and deliver a processed sample for detection. We are developing techniques for sample purification, mixing, and filtration that would be useful to many applications including immunologic and nucleic acid assays. Many of these fluidic functions are accomplished with acoustic radiation pressure or dielectrophoresis. We are integrating these technologies into packaged systems with pumps and valves to control fluid flow through the fluidic circuit.

Original language	English (US)
Title of host publication	Proceedings of SPIE - The International Society for Optical Engineering
Editors	C H Mastrangelo, H Becker
Pages	83-89
Number of pages	7
Volume	4560
DOIs	https://doi.org/10.1117/12.443043
State	Published - 2001
Externally published	Yes
Event	Microfluidics and BioMEMS - San Francisco, CA, United States Duration: Oct 22 2001 → Oct 24 2001

Other

Other	Microfluidics and BioMEMS
Country	United States
City	San Francisco, CA
Period	10/22/01 → 10/24/01

Keywords

Dielectrophoresis
MEMS
Microfluidics
Sample handling

ASJC Scopus subject areas

Electrical and Electronic Engineering
Condensed Matter Physics

Access to Document

10.1117/12.443043

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Cite this

Visuri, S., Benett, W., Bettencourt, K., Chang, J. T., Fisher, K., Hamilton, J., Krulevitch, P., Park, C., Stockton, C., Tarte, L., Wang, A., & Wilson, T. (2001). Microfluidic sample preparation for immunoassays. In C. H. Mastrangelo, & H. Becker (Eds.), Proceedings of SPIE - The International Society for Optical Engineering (Vol. 4560, pp. 83-89) https://doi.org/10.1117/12.443043

Microfluidic sample preparation for immunoassays. / Visuri, Steven; Benett, William; Bettencourt, Kerry; Chang, John T; Fisher, Karl; Hamilton, Julie; Krulevitch, Peter; Park, Christina; Stockton, Cheryl; Tarte, Lisa; Wang, Amy; Wilson, Thomas.

Proceedings of SPIE - The International Society for Optical Engineering. ed. / C H Mastrangelo; H Becker. Vol. 4560 2001. p. 83-89.

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Visuri, S, Benett, W, Bettencourt, K, Chang, JT, Fisher, K, Hamilton, J, Krulevitch, P, Park, C, Stockton, C, Tarte, L, Wang, A & Wilson, T 2001, Microfluidic sample preparation for immunoassays. in CH Mastrangelo & H Becker (eds), Proceedings of SPIE - The International Society for Optical Engineering. vol. 4560, pp. 83-89, Microfluidics and BioMEMS, San Francisco, CA, United States, 10/22/01. https://doi.org/10.1117/12.443043

Visuri, Steven ; Benett, William ; Bettencourt, Kerry ; Chang, John T ; Fisher, Karl ; Hamilton, Julie ; Krulevitch, Peter ; Park, Christina ; Stockton, Cheryl ; Tarte, Lisa ; Wang, Amy ; Wilson, Thomas. / Microfluidic sample preparation for immunoassays. Proceedings of SPIE - The International Society for Optical Engineering. editor / C H Mastrangelo ; H Becker. Vol. 4560 2001. pp. 83-89

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