Microevolution of the direct repeat locus of Mycobacterium tuberculosis in a strain prevalent in San Francisco

Roxanne S. Aga, Elizabeth Fair, Neil F. Abernethy, Kathryn DeRiemer, E. Antonio Paz, L. Masae Kawamura, Peter M. Small, Midori Kato-Maeda

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

We describe a microevolutionary event of a prevalent strain of Mycobacterium tuberculosis that caused two outbreaks in San Francisco. During the second outbreak, a direct variable repeat was lost. We discuss the mechanisms of this change and the implications of analyzing multiple genetic loci in this context.

Original languageEnglish (US)
Pages (from-to)1558-1560
Number of pages3
JournalJournal of Clinical Microbiology
Volume44
Issue number4
DOIs
StatePublished - Apr 2006

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San Francisco
Nucleic Acid Repetitive Sequences
Mycobacterium tuberculosis
Disease Outbreaks
Genetic Loci

ASJC Scopus subject areas

  • Microbiology (medical)
  • Microbiology

Cite this

Aga, R. S., Fair, E., Abernethy, N. F., DeRiemer, K., Paz, E. A., Kawamura, L. M., ... Kato-Maeda, M. (2006). Microevolution of the direct repeat locus of Mycobacterium tuberculosis in a strain prevalent in San Francisco. Journal of Clinical Microbiology, 44(4), 1558-1560. https://doi.org/10.1128/JCM.44.4.1558-1560.2006

Microevolution of the direct repeat locus of Mycobacterium tuberculosis in a strain prevalent in San Francisco. / Aga, Roxanne S.; Fair, Elizabeth; Abernethy, Neil F.; DeRiemer, Kathryn; Paz, E. Antonio; Kawamura, L. Masae; Small, Peter M.; Kato-Maeda, Midori.

In: Journal of Clinical Microbiology, Vol. 44, No. 4, 04.2006, p. 1558-1560.

Research output: Contribution to journalArticle

Aga, RS, Fair, E, Abernethy, NF, DeRiemer, K, Paz, EA, Kawamura, LM, Small, PM & Kato-Maeda, M 2006, 'Microevolution of the direct repeat locus of Mycobacterium tuberculosis in a strain prevalent in San Francisco', Journal of Clinical Microbiology, vol. 44, no. 4, pp. 1558-1560. https://doi.org/10.1128/JCM.44.4.1558-1560.2006
Aga, Roxanne S. ; Fair, Elizabeth ; Abernethy, Neil F. ; DeRiemer, Kathryn ; Paz, E. Antonio ; Kawamura, L. Masae ; Small, Peter M. ; Kato-Maeda, Midori. / Microevolution of the direct repeat locus of Mycobacterium tuberculosis in a strain prevalent in San Francisco. In: Journal of Clinical Microbiology. 2006 ; Vol. 44, No. 4. pp. 1558-1560.
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