Microevolution of the direct repeat locus of Mycobacterium tuberculosis in a strain prevalent in San Francisco

Roxanne S. Aga, Elizabeth Fair, Neil F. Abernethy, Kathryn DeRiemer, E. Antonio Paz, L. Masae Kawamura, Peter M. Small, Midori Kato-Maeda

Research output: Contribution to journalArticlepeer-review

8 Scopus citations

Abstract

We describe a microevolutionary event of a prevalent strain of Mycobacterium tuberculosis that caused two outbreaks in San Francisco. During the second outbreak, a direct variable repeat was lost. We discuss the mechanisms of this change and the implications of analyzing multiple genetic loci in this context.

Original languageEnglish (US)
Pages (from-to)1558-1560
Number of pages3
JournalJournal of Clinical Microbiology
Volume44
Issue number4
DOIs
StatePublished - Apr 2006

ASJC Scopus subject areas

  • Microbiology (medical)
  • Microbiology

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