Microdialysis as an approach to quantitate the release of neuropeptides

Susan De Mesquita, Margery C. Beinfeld, Jacqueline Crawley

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

DeMesquita, Susan, Margery C Beinfeld and Jacqueline N Crawley: Microdialysis as an Approach to Quantitate the Release of Neuropeptides Prog Neuro-Psychopharmacol & Biol Psychiat 1990, 14 (Suppl):S5-S15. 1. 1. In vivo microdialysis was performed on anesthetized and awake rats to measured release of cholecystokinin from the posterior nucleus accumbens. 2. 2. Basal levels of cholecystokinin were detectable by radioimmunoassay in some, but not all animals. 3. 3. Recovery through the microdialysis probe ranged from 0.1-2.4% for cholecystokinin, suggesting practical limitations to this approach with present technology.

Original languageEnglish (US)
JournalProgress in Neuropsychopharmacology and Biological Psychiatry
Volume14
Issue numberSUPPL. 1
DOIs
StatePublished - 1990
Externally publishedYes

Fingerprint

Cholecystokinin
Microdialysis
Neuropeptides
Nucleus Accumbens
Radioimmunoassay
Technology

Keywords

  • cholecystokinin
  • microdialysis
  • neuropeptides
  • nucleus accumbens

ASJC Scopus subject areas

  • Biological Psychiatry
  • Pharmacology

Cite this

Microdialysis as an approach to quantitate the release of neuropeptides. / Mesquita, Susan De; Beinfeld, Margery C.; Crawley, Jacqueline.

In: Progress in Neuropsychopharmacology and Biological Psychiatry, Vol. 14, No. SUPPL. 1, 1990.

Research output: Contribution to journalArticle

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