Microdialysis as an approach to quantitate the release of neuropeptides

Susan De Mesquita, Margery C. Beinfeld, Jacqueline Crawley

Research output: Contribution to journalArticlepeer-review

11 Scopus citations


DeMesquita, Susan, Margery C Beinfeld and Jacqueline N Crawley: Microdialysis as an Approach to Quantitate the Release of Neuropeptides Prog Neuro-Psychopharmacol & Biol Psychiat 1990, 14 (Suppl):S5-S15. 1. 1. In vivo microdialysis was performed on anesthetized and awake rats to measured release of cholecystokinin from the posterior nucleus accumbens. 2. 2. Basal levels of cholecystokinin were detectable by radioimmunoassay in some, but not all animals. 3. 3. Recovery through the microdialysis probe ranged from 0.1-2.4% for cholecystokinin, suggesting practical limitations to this approach with present technology.

Original languageEnglish (US)
JournalProgress in Neuropsychopharmacology and Biological Psychiatry
Issue numberSUPPL. 1
StatePublished - 1990
Externally publishedYes


  • cholecystokinin
  • microdialysis
  • neuropeptides
  • nucleus accumbens

ASJC Scopus subject areas

  • Biological Psychiatry
  • Pharmacology


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