Microdialysis as an approach to quantitate the release of neuropeptides

Susan De Mesquita, Margery C. Beinfeld, Jacqueline Crawley

Research output: Contribution to journalArticle

11 Scopus citations

Abstract

DeMesquita, Susan, Margery C Beinfeld and Jacqueline N Crawley: Microdialysis as an Approach to Quantitate the Release of Neuropeptides Prog Neuro-Psychopharmacol & Biol Psychiat 1990, 14 (Suppl):S5-S15. 1. 1. In vivo microdialysis was performed on anesthetized and awake rats to measured release of cholecystokinin from the posterior nucleus accumbens. 2. 2. Basal levels of cholecystokinin were detectable by radioimmunoassay in some, but not all animals. 3. 3. Recovery through the microdialysis probe ranged from 0.1-2.4% for cholecystokinin, suggesting practical limitations to this approach with present technology.

Original languageEnglish (US)
JournalProgress in Neuropsychopharmacology and Biological Psychiatry
Volume14
Issue numberSUPPL. 1
DOIs
StatePublished - 1990
Externally publishedYes

Keywords

  • cholecystokinin
  • microdialysis
  • neuropeptides
  • nucleus accumbens

ASJC Scopus subject areas

  • Biological Psychiatry
  • Pharmacology

Fingerprint Dive into the research topics of 'Microdialysis as an approach to quantitate the release of neuropeptides'. Together they form a unique fingerprint.

  • Cite this