Abstract
This work describes the synthesis of (R)-Nifenalol® based on an enantioconvergent chemoenzymatic hydrolysis of para-nitrostyrene oxide. A mathematical approach is devised which allowed to optimize the process.
Original language | English (US) |
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Pages (from-to) | 9707-9714 |
Number of pages | 8 |
Journal | Tetrahedron |
Volume | 53 |
Issue number | 28 |
DOIs | |
State | Published - Jul 14 1997 |
Externally published | Yes |
ASJC Scopus subject areas
- Biochemistry
- Organic Chemistry
- Drug Discovery