Abstract
This work describes the synthesis of (R)-Nifenalol® based on an enantioconvergent chemoenzymatic hydrolysis of para-nitrostyrene oxide. A mathematical approach is devised which allowed to optimize the process.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 9707-9714 |
| Number of pages | 8 |
| Journal | Tetrahedron |
| Volume | 53 |
| Issue number | 28 |
| DOIs | |
| State | Published - Jul 14 1997 |
| Externally published | Yes |
Fingerprint
ASJC Scopus subject areas
- Biochemistry
- Organic Chemistry
- Drug Discovery
Cite this
Microbiological transformations 37. An enantioconvergent synthesis of the β-blocker (R)-Nifenalol® using a combined chemoenzymatic approach. / Pedragosa-Moreau, S.; Morisseau, C.; Baratti, J.; Zylber, J.; Archelas, A.; Furstoss, R.
In: Tetrahedron, Vol. 53, No. 28, 14.07.1997, p. 9707-9714.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Microbiological transformations 37. An enantioconvergent synthesis of the β-blocker (R)-Nifenalol® using a combined chemoenzymatic approach
AU - Pedragosa-Moreau, S.
AU - Morisseau, C.
AU - Baratti, J.
AU - Zylber, J.
AU - Archelas, A.
AU - Furstoss, R.
PY - 1997/7/14
Y1 - 1997/7/14
N2 - This work describes the synthesis of (R)-Nifenalol® based on an enantioconvergent chemoenzymatic hydrolysis of para-nitrostyrene oxide. A mathematical approach is devised which allowed to optimize the process.
AB - This work describes the synthesis of (R)-Nifenalol® based on an enantioconvergent chemoenzymatic hydrolysis of para-nitrostyrene oxide. A mathematical approach is devised which allowed to optimize the process.
UR - http://www.scopus.com/inward/record.url?scp=0030848933&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0030848933&partnerID=8YFLogxK
U2 - 10.1016/S0040-4020(97)00639-X
DO - 10.1016/S0040-4020(97)00639-X
M3 - Article
AN - SCOPUS:0030848933
VL - 53
SP - 9707
EP - 9714
JO - Tetrahedron
JF - Tetrahedron
SN - 0040-4020
IS - 28
ER -