Abstract
Two chiral quaternary carbon-containing fragments suitable for elaboration to the briaran diterpenes were obtained by regioselective methylation of functionalized 3,3-disubstituted 2,3-epoxy-1-ols. The factors which favor methylation at the more hindered position of a trisubstituted 2,3-epoxy alcohol were determined.
Original language | English (US) |
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Pages (from-to) | 7429-7444 |
Number of pages | 16 |
Journal | Tetrahedron |
Volume | 53 |
Issue number | 22 |
DOIs | |
State | Published - Jun 2 1997 |
ASJC Scopus subject areas
- Biochemistry
- Organic Chemistry
- Drug Discovery