Abstract
We describe a simple, rapid, and semiautomated method of MR analysis based on mathematical modeling of MR pixel intensity histograms. The method is shown to be accurate and reliable for regional analysis of brain, central, and subarachnoid CSF volumes. Application of the method to five young and six older subjects revealed significant age-related changes in regional brain volumes whereas no difference was found for traced central CSF volumes or subarachnoid CSF volumes. We conclude that this is a simple method that can be applied to further studies of quantification of brain structure in healthy aging and brain disease.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 274-284 |
| Number of pages | 11 |
| Journal | Journal of Computer Assisted Tomography |
| Volume | 16 |
| Issue number | 2 |
| State | Published - 1992 |
| Externally published | Yes |
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Keywords
- Aging
- Brain, volume
- Magnetic resonance imaging, techniques
ASJC Scopus subject areas
- Radiology Nuclear Medicine and imaging
- Radiological and Ultrasound Technology
Cite this
Method for quantification of brain, ventricular, and subarachnoid CSF volumes from MR images. / DeCarli, Charles; Maisog, J.; Murphy, D. G M; Teichberg, D.; Rapoport, S. I.; Horwitz, B.
In: Journal of Computer Assisted Tomography, Vol. 16, No. 2, 1992, p. 274-284.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Method for quantification of brain, ventricular, and subarachnoid CSF volumes from MR images
AU - DeCarli, Charles
AU - Maisog, J.
AU - Murphy, D. G M
AU - Teichberg, D.
AU - Rapoport, S. I.
AU - Horwitz, B.
PY - 1992
Y1 - 1992
N2 - We describe a simple, rapid, and semiautomated method of MR analysis based on mathematical modeling of MR pixel intensity histograms. The method is shown to be accurate and reliable for regional analysis of brain, central, and subarachnoid CSF volumes. Application of the method to five young and six older subjects revealed significant age-related changes in regional brain volumes whereas no difference was found for traced central CSF volumes or subarachnoid CSF volumes. We conclude that this is a simple method that can be applied to further studies of quantification of brain structure in healthy aging and brain disease.
AB - We describe a simple, rapid, and semiautomated method of MR analysis based on mathematical modeling of MR pixel intensity histograms. The method is shown to be accurate and reliable for regional analysis of brain, central, and subarachnoid CSF volumes. Application of the method to five young and six older subjects revealed significant age-related changes in regional brain volumes whereas no difference was found for traced central CSF volumes or subarachnoid CSF volumes. We conclude that this is a simple method that can be applied to further studies of quantification of brain structure in healthy aging and brain disease.
KW - Aging
KW - Brain, volume
KW - Magnetic resonance imaging, techniques
UR - http://www.scopus.com/inward/record.url?scp=0026561468&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0026561468&partnerID=8YFLogxK
M3 - Article
C2 - 1545026
AN - SCOPUS:0026561468
VL - 16
SP - 274
EP - 284
JO - Journal of Computer Assisted Tomography
JF - Journal of Computer Assisted Tomography
SN - 0363-8715
IS - 2
ER -