Metastatic carcinoma of probable transitional cell origin in 66 free-living California sea lions (Zalophus californianus), 1979 to 1994

F. M D Gulland, J. G. Trupkiewicz, T. R. Spraker, Linda J Lowenstine

Research output: Contribution to journalArticle

68 Citations (Scopus)

Abstract

Sixty-six (18%) cases of widely metastatic carcinoma of probable transitional cell origin were identified in 370 California sea lions (Zalophus californianus) stranded alive along the central California (USA) coast, between January 1979 and December 1994. Live animals were usually emaciated and anorectic, with perineal edema and occasionally hind-flipper paralysis or paresis. Large yellow caseous masses were observed in the sub-lumbar lymph nodes, often extending around the ureters resulting in hydroureter. Histologically, metastases were usually widespread, and the primary neoplastic focus undetectable. This is the highest reported prevalence among necropsied animals of neoplasia in a pinniped population to date.

Original languageEnglish (US)
Pages (from-to)250-258
Number of pages9
JournalJournal of Wildlife Diseases
Volume32
Issue number2
StatePublished - Apr 1996

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Sea Lions
pinniped
Transitional Cell Carcinoma
carcinoma
Pinnipedia
Appetite Depressants
ureter
paresis
animal
Paresis
paralysis
Ureter
Paralysis
metastasis
edema
lymph nodes
Edema
animals
Lymph Nodes
cells

Keywords

  • California
  • California sea lion
  • Free-ranging
  • Neoplasia
  • Pinniped
  • Transitional cell carcinoma
  • Zalophus californianus

ASJC Scopus subject areas

  • veterinary(all)

Cite this

Metastatic carcinoma of probable transitional cell origin in 66 free-living California sea lions (Zalophus californianus), 1979 to 1994. / Gulland, F. M D; Trupkiewicz, J. G.; Spraker, T. R.; Lowenstine, Linda J.

In: Journal of Wildlife Diseases, Vol. 32, No. 2, 04.1996, p. 250-258.

Research output: Contribution to journalArticle

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