Metastasis of Osteosarcoma to the Abdomen: A Report of Two Cases and a Review of the Literature

Robert Serpico, Jeffrey Brown, Alan Blank, Kevin Jones, R. Lor Randall, John Groundland

Research output: Contribution to journalReview articlepeer-review

1 Scopus citations


Two cases of primary distal femur osteosarcoma with subsequent metastasis to the abdomen are presented. In both cases, the development of abdominal metastasis was quickly followed by patient decline and death. A review of the literature was performed, assessing the presentation and survival of patients with osteosarcoma metastasized to the abdomen. As illustrated by the current cases and the literature review, abdominal metastasis in osteosarcoma is often a late manifestation and terminal prognostic indicator. Nonetheless, early detection and prompt intervention of this less common site of disease metastasis may improve patient care and palliative therapy.

Original languageEnglish (US)
Pages (from-to)647-658
Number of pages12
JournalCase Reports in Oncology
StateAccepted/In press - 2021


  • Abdominal metastasis
  • Distant metastasis
  • Metastatic osteosarcoma
  • Nonpulmonary osteosarcoma metastasis

ASJC Scopus subject areas

  • Oncology


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