Mercury-free mouse ICSI with rotationally oscillating drill (Ros-Drill©)

Ali Fuat Ergenc, Ming Wen Li, Mehmet Toner, John D. Biggers, Kevin C K Lloyd, Nejat Olgac

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

ICSI (intracytoplasmic sperm injection) is an important and commonly used assisted reproductive technology (ART) in humans and animals. However, conventional ICSI has proven to be difficult and inefficient, especially in mice. Fortunately, the application of piezo-electric technology to assist the injection process has made ICSI more effective and efficient in recent years. Despite this advance, the pipette tip is unstable in response to the force exerted by the piezoelectric pulse during injection. To some extent, this instability can be mitigated by the use of mercury, which is highly toxic. In an effort to overcome these hurdles, we developed and tested a completely different and mercury-free technology, called the "Ros-Drill

Original languageEnglish (US)
Title of host publicationBioengineering, Proceedings of the Northeast Conference
DOIs
StatePublished - 2009
EventIEEE 35th Annual Northeast Bioengineering Conference, NEBEC 2009 - Boston, MA, United States
Duration: Apr 3 2009Apr 5 2009

Other

OtherIEEE 35th Annual Northeast Bioengineering Conference, NEBEC 2009
CountryUnited States
CityBoston, MA
Period4/3/094/5/09

ASJC Scopus subject areas

  • Bioengineering

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    Ergenc, A. F., Li, M. W., Toner, M., Biggers, J. D., Lloyd, K. C. K., & Olgac, N. (2009). Mercury-free mouse ICSI with rotationally oscillating drill (Ros-Drill©). In Bioengineering, Proceedings of the Northeast Conference [4967747] https://doi.org/10.1109/NEBC.2009.4967747