Meningoencephalitis caused by Naegleria fowleri in cattle of northeast Brazil

Luciano A. Pimentel, Antônio Flávio M Dantas, Francisco A Uzal, Franklin Riet-Correa

Research output: Contribution to journalArticlepeer-review

14 Scopus citations


Primary amoebic meningoencephalitis is an acute disease of the central nervous system of humans and animals caused by Naegleria fowleri. This report describes a case of meningoencephalitis caused by N. fowleri in a crossbred, one-year-old bovine with progressive neurological signs. At necropsy there was thickening of the meninges and multifocal areas of malacia in the thalamus, caudal and rostral colliculi, parietal and occipital cortex, and cerebellum. Histologically there was multifocal necrosupurative meningoencephalitis associated with areas of malacia containing amoebic trophozoites. Immunohistochemistry of the brain was positive for N. fowleri. The disease should be included among the differential diagnosis of diseases of the central nervous system in cattle in areas where animals are exposed to hot, stagnant water.

Original languageEnglish (US)
Pages (from-to)811-812
Number of pages2
JournalResearch in Veterinary Science
Issue number2
StatePublished - Oct 2012


  • Amoeba
  • Cattle
  • Diseases of the central nervous system
  • Trophozoites

ASJC Scopus subject areas

  • veterinary(all)


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