Memory and regional cerebral blood flow in mildly symptomatic Alzheimer's disease

Bruce R Reed; W. J. Jagust; J. P. Seab; B. A. Ober

Memory and regional cerebral blood flow in mildly symptomatic Alzheimer's disease

Bruce R Reed, W. J. Jagust, J. P. Seab, B. A. Ober

Neurology

Research output: Contribution to journal › Article › peer-review

72 Scopus citations

Abstract

We performed SPECT perfusion imaging and memory testing with mildly and moderately demented Alzheimer's disease (AD) patients and with healthy controls. All patients had memory abnormalities, but 5 of the 21 patients had neither temporal nor parietal perfusion abnormalities, indicating that temporoparietal blood flow may be normal at a point when memory is pathologic and the clinical diagnosis of AD is possible.

Original language	English (US)
Pages (from-to)	1537-1539
Number of pages	3
Journal	Neurology
Volume	39
Issue number	11
State	Published - 1989

ASJC Scopus subject areas

Neuroscience(all)

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title = "Memory and regional cerebral blood flow in mildly symptomatic Alzheimer's disease",

abstract = "We performed SPECT perfusion imaging and memory testing with mildly and moderately demented Alzheimer's disease (AD) patients and with healthy controls. All patients had memory abnormalities, but 5 of the 21 patients had neither temporal nor parietal perfusion abnormalities, indicating that temporoparietal blood flow may be normal at a point when memory is pathologic and the clinical diagnosis of AD is possible.",

author = "Reed, {Bruce R} and Jagust, {W. J.} and Seab, {J. P.} and Ober, {B. A.}",

year = "1989",

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AU - Jagust, W. J.

AU - Seab, J. P.

AU - Ober, B. A.

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N2 - We performed SPECT perfusion imaging and memory testing with mildly and moderately demented Alzheimer's disease (AD) patients and with healthy controls. All patients had memory abnormalities, but 5 of the 21 patients had neither temporal nor parietal perfusion abnormalities, indicating that temporoparietal blood flow may be normal at a point when memory is pathologic and the clinical diagnosis of AD is possible.

AB - We performed SPECT perfusion imaging and memory testing with mildly and moderately demented Alzheimer's disease (AD) patients and with healthy controls. All patients had memory abnormalities, but 5 of the 21 patients had neither temporal nor parietal perfusion abnormalities, indicating that temporoparietal blood flow may be normal at a point when memory is pathologic and the clinical diagnosis of AD is possible.

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