Memory and regional cerebral blood flow in mildly symptomatic Alzheimer's disease

Bruce R Reed, W. J. Jagust, J. P. Seab, B. A. Ober

Research output: Contribution to journalArticle

72 Scopus citations

Abstract

We performed SPECT perfusion imaging and memory testing with mildly and moderately demented Alzheimer's disease (AD) patients and with healthy controls. All patients had memory abnormalities, but 5 of the 21 patients had neither temporal nor parietal perfusion abnormalities, indicating that temporoparietal blood flow may be normal at a point when memory is pathologic and the clinical diagnosis of AD is possible.

Original languageEnglish (US)
Pages (from-to)1537-1539
Number of pages3
JournalNeurology
Volume39
Issue number11
StatePublished - 1989

ASJC Scopus subject areas

  • Neuroscience(all)

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    Reed, B. R., Jagust, W. J., Seab, J. P., & Ober, B. A. (1989). Memory and regional cerebral blood flow in mildly symptomatic Alzheimer's disease. Neurology, 39(11), 1537-1539.