Meiotic recombination

Research output: Chapter in Book/Report/Conference proceedingChapter

5 Scopus citations

Abstract

Crossover recombination is essential for homolog segregation during meiosis. In contrast to spontaneous mitotic recombination, meiotic recombination is intrinsic being initiated by the programmed formation of DNA double-strand-breaks. In addition, the tendencies of the core recombination machinery to utilize a sister-chromatid template and to produce a noncrossover outcome are counteracted by meiosis-specific factors, which ultimately ensure the formation of at least one crossover per homolog.

Original languageEnglish (US)
Title of host publicationTopics in Current Genetics
Pages443-467
Number of pages25
Volume17
DOIs
StatePublished - 2007

Publication series

NameTopics in Current Genetics
Volume17
ISSN (Print)16102096
ISSN (Electronic)16106970

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ASJC Scopus subject areas

  • Genetics
  • Cell Biology
  • Molecular Biology
  • Developmental Biology

Cite this

Hunter, N. (2007). Meiotic recombination. In Topics in Current Genetics (Vol. 17, pp. 443-467). (Topics in Current Genetics; Vol. 17). https://doi.org/10.1007/4735_2006_0215