Medical management of recurrent eosinophilic granuloma in two black rhinoceros (Diceros Bicornis)

Greg T. Bishop, Jeffery R. Zuba, Allan P. Pessier, Jane Hopper, Gloria Kendall, Rod A.W. Rosychuk, K G Magdesian

Research output: Contribution to journalArticle

Abstract

Recurrent eosinophilic granuloma (EG) in two captive eastern black rhinoceros (Diceros bicornis michaeli) was effectively managed with glucocorticoids and antihistamines. The first case was a female and the second case was a male. The animals were housed at separate institutions and initially presented with hemorrhagic oral lesions. Multifocal lesions occurred in the second case. Multiple biopsies were taken from each animal, all of which were consistent with EG. Each animal was anesthetized multiple times for surgical treatment but experienced frequent recurrence. Due to lack of response to therapy and the risks and adverse events associated with repeated anesthesia, medical treatment was initiated in both cases using a tapering dose of oral dexamethasone. The lesions dramatically improved, but would recur frequently after treatment. Hydroxyzine, an oral antihistamine, greatly reduced the incidence and severity of the lesions. Medical management with glucocorticoids and antihistamines minimized stressful anesthetic events in both cases and contributed to the successful management of this recurrent disease. The exact pathogenesis of EG in black rhinoceros remains unknown but response to antihistamines suggests an allergic etiology.

Original languageEnglish (US)
Pages (from-to)855-861
Number of pages7
JournalJournal of Zoo and Wildlife Medicine
Volume47
Issue number3
DOIs
StatePublished - Sep 1 2016
Externally publishedYes

Fingerprint

Diceros bicornis
antihistamines
Eosinophilic Granuloma
Histamine Antagonists
granuloma
lesions (animal)
mouth
glucocorticoids
Glucocorticoids
Hydroxyzine
animals
medical treatment
dexamethasone
Disease Management
anesthetics
Dexamethasone
etiology
Anesthetics
biopsy
anesthesia

Keywords

  • Allergy
  • black rhinoceros
  • dexamethasone
  • Diceros bicornis
  • eosinophilic granuloma
  • hydroxyzine

ASJC Scopus subject areas

  • Animal Science and Zoology
  • veterinary(all)

Cite this

Medical management of recurrent eosinophilic granuloma in two black rhinoceros (Diceros Bicornis). / Bishop, Greg T.; Zuba, Jeffery R.; Pessier, Allan P.; Hopper, Jane; Kendall, Gloria; Rosychuk, Rod A.W.; Magdesian, K G.

In: Journal of Zoo and Wildlife Medicine, Vol. 47, No. 3, 01.09.2016, p. 855-861.

Research output: Contribution to journalArticle

Bishop, Greg T. ; Zuba, Jeffery R. ; Pessier, Allan P. ; Hopper, Jane ; Kendall, Gloria ; Rosychuk, Rod A.W. ; Magdesian, K G. / Medical management of recurrent eosinophilic granuloma in two black rhinoceros (Diceros Bicornis). In: Journal of Zoo and Wildlife Medicine. 2016 ; Vol. 47, No. 3. pp. 855-861.
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