Medical comorbidity in late-life bipolar disorder

Research output: Chapter in Book/Report/Conference proceedingChapter

4 Scopus citations


Mr. P. is an 80-year-old man with a 50-year history of bipolar disorder. The disorder was diagnosed in 1955, when, at age 29, he had his first manic episode. During his younger adulthood he had several manic and depressive episodes, questionable adherence to his prescribed medication, and alcohol abuse. In his fifties, he stopped using alcohol and was maintained on lithium at 1,200 mg/day, with good results. Then, in 1995, during hospitalization for resection of a benign rectal tumor, Mr. P. became manic after reduction of his lithium dose. Surgery staff noted that he had an elevated mood, labile emotions, and hypersexuality. His mania abated with the resumption of his usual dose of lithium and with the addition of thiothixene; however, one month later he developed symptoms of a severe major depression and received electroconvulsive therapy (ECT) treatments as an inpatient. When Mr. P was discharged he was taking risperidone, which was tapered and discontinued while he was an outpatient; he eventually began taking lithium again, at 900 mg/day.

Original languageEnglish (US)
Title of host publicationBipolar Disorder in Later Life
PublisherThe Johns Hopkins University Press
Number of pages20
ISBN (Print)9780801885815
StatePublished - Dec 1 2007
Externally publishedYes

ASJC Scopus subject areas

  • Social Sciences(all)


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