Mechanisms of contrast agent destruction

James E. Chômas, Paul Dayton, John Alien, Karen Morgan, Katherine W. Ferrara

Research output: Contribution to journalArticlepeer-review

309 Scopus citations


Various applications of contrast-assisted ultrasound require controlled destruction of contrast agent microbubbles. Mechanisms of fragmentation, acoustically driven diffusion, and static diffusion related to microbubble destruction are studied. Fragmentation is found responsible for rapid destruction of contrast agents on a time scale of microseconds.

Original languageEnglish (US)
Pages (from-to)232-248
Number of pages17
JournalIEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
Issue number1
StatePublished - Jan 2001
Externally publishedYes

ASJC Scopus subject areas

  • Electrical and Electronic Engineering
  • Acoustics and Ultrasonics


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