Mechanisms of cell synchronization in epileptiform activity

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8 Scopus citations


Researchers have long considered the potential roles of electronic synapses and ephaptic interactions in the central nervous system (CNS). They are obvious candidates for producing the synchronization of neuronal populations which characterizes epileptiform discharge. Are these primary mechanisms or do they simply modulate other, more powerful, forces? Can chemical synaptic connectivity alone account for spontaneous, rhythmic, synchronized discharge? Current research into basic mechanisms underlying epileptogenesis provides some interesting observations relevant to these questions.

Original languageEnglish (US)
Pages (from-to)157
Number of pages1
JournalTrends in Neurosciences
Issue numberC
StatePublished - 1983
Externally publishedYes

ASJC Scopus subject areas

  • Neuroscience(all)


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