Abstract
Researchers have long considered the potential roles of electronic synapses and ephaptic interactions in the central nervous system (CNS). They are obvious candidates for producing the synchronization of neuronal populations which characterizes epileptiform discharge. Are these primary mechanisms or do they simply modulate other, more powerful, forces? Can chemical synaptic connectivity alone account for spontaneous, rhythmic, synchronized discharge? Current research into basic mechanisms underlying epileptogenesis provides some interesting observations relevant to these questions.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 157 |
| Number of pages | 1 |
| Journal | Trends in Neurosciences |
| Volume | 6 |
| Issue number | C |
| DOIs | |
| State | Published - 1983 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Neuroscience(all)
Cite this
Mechanisms of cell synchronization in epileptiform activity. / Schwartzkroin, Philip A.
In: Trends in Neurosciences, Vol. 6, No. C, 1983, p. 157.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Mechanisms of cell synchronization in epileptiform activity
AU - Schwartzkroin, Philip A
PY - 1983
Y1 - 1983
N2 - Researchers have long considered the potential roles of electronic synapses and ephaptic interactions in the central nervous system (CNS). They are obvious candidates for producing the synchronization of neuronal populations which characterizes epileptiform discharge. Are these primary mechanisms or do they simply modulate other, more powerful, forces? Can chemical synaptic connectivity alone account for spontaneous, rhythmic, synchronized discharge? Current research into basic mechanisms underlying epileptogenesis provides some interesting observations relevant to these questions.
AB - Researchers have long considered the potential roles of electronic synapses and ephaptic interactions in the central nervous system (CNS). They are obvious candidates for producing the synchronization of neuronal populations which characterizes epileptiform discharge. Are these primary mechanisms or do they simply modulate other, more powerful, forces? Can chemical synaptic connectivity alone account for spontaneous, rhythmic, synchronized discharge? Current research into basic mechanisms underlying epileptogenesis provides some interesting observations relevant to these questions.
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UR - http://www.scopus.com/inward/citedby.url?scp=0020641583&partnerID=8YFLogxK
U2 - 10.1016/0166-2236(83)90074-7
DO - 10.1016/0166-2236(83)90074-7
M3 - Article
AN - SCOPUS:0020641583
VL - 6
SP - 157
JO - Trends in Neurosciences
JF - Trends in Neurosciences
SN - 0378-5912
IS - C
ER -