Abstract
To understand the biologic processes involved in transmission of HIV, we examined the genital tracts of chronically infected female macaques and localized SIV-infected cells. SIV was found in the genital tract of 12 of 16 animals and SIV-infected cells were located in the cervix and vagina. Inoculation of cell-free SIV into the blind vaginal pouch of hysterectomized macaques resulted in systemic infection. We propose a hypothesis to explain the early events in the genital transmission of SIV.
Original language | English (US) |
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Pages (from-to) | 64-68 |
Number of pages | 5 |
Journal | Journal of Medical Primatology |
Volume | 21 |
Issue number | 2-3 |
State | Published - Feb 1992 |
ASJC Scopus subject areas
- Animal Science and Zoology
- veterinary(all)