Mechanical analysis of arterial plaques in native geometry with OCT wall motion analysis

Claire Robertson, Andrew E. Heidari, Zhongping Chen, Steven George

Research output: Contribution to journalArticle

4 Scopus citations

Abstract

The mechanical behavior of an atherosclerotic plaque may encode information about the type, composition, and vulnerability to rupture. Human arterial segments with varying plaque burden were analyzed ex vivo with optical coherence tomography (OCT) to determine plaque type and to determine compliance during pulsatile inflation in their native geometry. Calcifications and lipid filled plaques showed markedly different compliance when analyzed with OCT wall motion analysis. There was also a trend towards increased circumferential variation in arterial compliance with increasing plaque burden.

Original languageEnglish (US)
Pages (from-to)755-758
Number of pages4
JournalJournal of Biomechanics
Volume47
Issue number3
DOIs
StatePublished - Feb 7 2014

Keywords

  • Atherosclerotic plaque
  • Compliance
  • Optical coherence tomography

ASJC Scopus subject areas

  • Biophysics
  • Orthopedics and Sports Medicine
  • Biomedical Engineering
  • Rehabilitation

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