Mechanical analysis of arterial plaques in native geometry with OCT wall motion analysis

Claire Robertson; Andrew E. Heidari; Zhongping Chen; Steven George

doi:10.1016/j.jbiomech.2013.11.010

Mechanical analysis of arterial plaques in native geometry with OCT wall motion analysis

Claire Robertson, Andrew E. Heidari, Zhongping Chen, Steven George

Biomedical Engineering

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

The mechanical behavior of an atherosclerotic plaque may encode information about the type, composition, and vulnerability to rupture. Human arterial segments with varying plaque burden were analyzed ex vivo with optical coherence tomography (OCT) to determine plaque type and to determine compliance during pulsatile inflation in their native geometry. Calcifications and lipid filled plaques showed markedly different compliance when analyzed with OCT wall motion analysis. There was also a trend towards increased circumferential variation in arterial compliance with increasing plaque burden.

Original language	English (US)
Pages (from-to)	755-758
Number of pages	4
Journal	Journal of Biomechanics
Volume	47
Issue number	3
DOIs	https://doi.org/10.1016/j.jbiomech.2013.11.010
State	Published - Feb 7 2014

Keywords

Atherosclerotic plaque
Compliance
Optical coherence tomography

ASJC Scopus subject areas

Biophysics
Orthopedics and Sports Medicine
Biomedical Engineering
Rehabilitation

Access to Document

10.1016/j.jbiomech.2013.11.010

Fingerprint Dive into the research topics of 'Mechanical analysis of arterial plaques in native geometry with OCT wall motion analysis'. Together they form a unique fingerprint.

Cite this

@article{39ee4708bef9489c842196b7584edfe3,

title = "Mechanical analysis of arterial plaques in native geometry with OCT wall motion analysis",

abstract = "The mechanical behavior of an atherosclerotic plaque may encode information about the type, composition, and vulnerability to rupture. Human arterial segments with varying plaque burden were analyzed ex vivo with optical coherence tomography (OCT) to determine plaque type and to determine compliance during pulsatile inflation in their native geometry. Calcifications and lipid filled plaques showed markedly different compliance when analyzed with OCT wall motion analysis. There was also a trend towards increased circumferential variation in arterial compliance with increasing plaque burden.",

keywords = "Atherosclerotic plaque, Compliance, Optical coherence tomography",

author = "Claire Robertson and Heidari, {Andrew E.} and Zhongping Chen and Steven George",

year = "2014",

month = feb,

day = "7",

doi = "10.1016/j.jbiomech.2013.11.010",

language = "English (US)",

volume = "47",

pages = "755--758",

journal = "Journal of Biomechanics",

issn = "0021-9290",

publisher = "Elsevier Limited",

number = "3",

}

TY - JOUR

T1 - Mechanical analysis of arterial plaques in native geometry with OCT wall motion analysis

AU - Robertson, Claire

AU - Heidari, Andrew E.

AU - Chen, Zhongping

AU - George, Steven

PY - 2014/2/7

Y1 - 2014/2/7

N2 - The mechanical behavior of an atherosclerotic plaque may encode information about the type, composition, and vulnerability to rupture. Human arterial segments with varying plaque burden were analyzed ex vivo with optical coherence tomography (OCT) to determine plaque type and to determine compliance during pulsatile inflation in their native geometry. Calcifications and lipid filled plaques showed markedly different compliance when analyzed with OCT wall motion analysis. There was also a trend towards increased circumferential variation in arterial compliance with increasing plaque burden.

AB - The mechanical behavior of an atherosclerotic plaque may encode information about the type, composition, and vulnerability to rupture. Human arterial segments with varying plaque burden were analyzed ex vivo with optical coherence tomography (OCT) to determine plaque type and to determine compliance during pulsatile inflation in their native geometry. Calcifications and lipid filled plaques showed markedly different compliance when analyzed with OCT wall motion analysis. There was also a trend towards increased circumferential variation in arterial compliance with increasing plaque burden.

KW - Atherosclerotic plaque

KW - Compliance

KW - Optical coherence tomography

UR - http://www.scopus.com/inward/record.url?scp=84892519351&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84892519351&partnerID=8YFLogxK

U2 - 10.1016/j.jbiomech.2013.11.010

DO - 10.1016/j.jbiomech.2013.11.010

M3 - Article

C2 - 24388166

AN - SCOPUS:84892519351

VL - 47

SP - 755

EP - 758

JO - Journal of Biomechanics

JF - Journal of Biomechanics

SN - 0021-9290

IS - 3

ER -