Measurement of pulmonary diffusing capacity for carbon monoxide and functional residual capacity during rebreathing in conscious thoroughbreds.

E. Aguilera-Tejéro, John Pascoe, T. C. Amis, C. J. Kurpershoek, M. J. Woliner

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

A rebreathing method for measurement of pulmonary diffusing capacity for carbon monoxide (DLCO) and functional residual capacity (FRC) was evaluated in conscious horses. Horses were manually ventilated through an endotracheal tube, using a custom-made syringe filled with a gas mixture containing 18-carbon monoxide (18CO) and helium (He). The 18CO and He concentrations were continuously monitored by use of a mass spectrometer connected to the rebreathing circuit. Values for DLCO and FRC were calculated from changes in the concentration of these 2 gases. In 11 Thoroughbreds, mean (+/- SD) DLCO was 330.3 +/- 56.9 ml.min-1 x mm of Hg-1, and FRC was 20.21 +/- 3.35 L. Body weight normalization yielded mean (+/- SD) values of 0.652 +/- 0.114 ml.min-1 x mm of Hg-1 x kg-1 for DLCO, and 39.9 +/- 6.4 ml.kg-1 for FRC.

Original languageEnglish (US)
Pages (from-to)1752-1757
Number of pages6
JournalAmerican Journal of Veterinary Research
Volume54
Issue number10
StatePublished - Oct 1 1993

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Pulmonary Diffusing Capacity
Functional Residual Capacity
carbon monoxide
Carbon Monoxide
helium
lungs
Helium
gases
Horses
horses
syringes
Gases
spectrometers
Syringes
body weight
Body Weight
methodology

ASJC Scopus subject areas

  • veterinary(all)

Cite this

Measurement of pulmonary diffusing capacity for carbon monoxide and functional residual capacity during rebreathing in conscious thoroughbreds. / Aguilera-Tejéro, E.; Pascoe, John; Amis, T. C.; Kurpershoek, C. J.; Woliner, M. J.

In: American Journal of Veterinary Research, Vol. 54, No. 10, 01.10.1993, p. 1752-1757.

Research output: Contribution to journalArticle

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