Measurement of lung density by x-ray computed tomography. Relation to lung mechanics in workers exposed to asbestos cement.

P. Wollmer, K. Jakobsson, M. Albin, U. Albrechtsson, K. Brauer, L. Eriksson, B. Jonson, S. Skerfving, Ulf Tylen

Research output: Contribution to journalArticle

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Abstract

We measured lung density by means of x-ray computed tomography and lung mechanics in 33 workers exposed to asbestos cement and in 39 normal subjects. The exposed group showed evidence of lung fibrosis with reduced static lung volumes and lung compliance, although only three subjects had signs of interstitial fibrosis at standard chest radiography. Lung density was significantly increased in the exposed workers compared to control subjects, with greater differences between nonsmokers than between smokers. Lung density correlated inversely with static lung volumes. There was no appreciable difference in the regional distribution of lung density between exposed workers and control subjects. We conclude that lung density is often increased in workers with mild asbestosis, even in the presence of a normal chest radiograph. Measurement of lung density may be of value in the evaluation of asbestos-exposed workers for assessment of the extent of parenchymal disease.

Original languageEnglish (US)
Pages (from-to)865-869
Number of pages5
JournalChest
Volume91
Issue number6
StatePublished - Jun 1987
Externally publishedYes

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

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    Wollmer, P., Jakobsson, K., Albin, M., Albrechtsson, U., Brauer, K., Eriksson, L., Jonson, B., Skerfving, S., & Tylen, U. (1987). Measurement of lung density by x-ray computed tomography. Relation to lung mechanics in workers exposed to asbestos cement. Chest, 91(6), 865-869.