Measurement issues in the use of cognitive neuroscience tasks in drug development for impaired cognition in schizophrenia: A report of the second consensus building conference of the CNTRICS initiative

Deanna M. Barch, Cameron S Carter

Research output: Contribution to journalArticle

32 Citations (Scopus)

Abstract

This overview describes the goals and objectives of the second conference conducted as part of the Cognitive Neuroscience Treatment Research to Improve Cognition in Schizophrenia (CNTRICS) initiative. This second conference was informed by a series of online surveys and brought together basic and clinical scientists from academia and industry to address the concerns central to each field of research. Our goal was to develop recommendations for future research addressing the psychometric and practical challenges involved in translating paradigms from cognitive neuroscience into tasks that are feasible for use in the treatment discovery and development process. In this overview article, we describe the series of talks that were presentations at the conference. This article serves as an introduction to the set of articles included in this special issue that provide overviews and discussions of the issues raised and the recommendations made in these talks and in the subsequent discussions at the meeting. In addition, we describe the online surveys conducted in the month before the conference that were used to obtain suggestions from the field as to important task selection criteria and to generate initial benchmark goals for psychometric development for cognitive neuroscience tasks.

Original languageEnglish (US)
Pages (from-to)613-618
Number of pages6
JournalSchizophrenia Bulletin
Volume34
Issue number4
DOIs
StatePublished - Jul 2008

Fingerprint

Cognition
Schizophrenia
Consensus
Research
Psychometrics
Pharmaceutical Preparations
Benchmarking
Patient Selection
Industry
Cognitive Neuroscience
Surveys and Questionnaires

Keywords

  • Pharmacology
  • Translation
  • Treatment

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Neuroscience(all)

Cite this

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