Measured concentrations of consumer product chemicals in California house dust: Implications for sources, exposure, and toxicity potential

Hyeong Moo Shin, Christoph Moschet, Thomas M. Young, Deborah H. Bennett

Research output: Contribution to journalArticle

Abstract

Household dust is a reservoir of various consumer product chemicals. Thus, characterizing comprehensive chemical profiles of house dust may help improve our understanding of residential chemical exposure. We have previously developed a method for detecting a broad spectrum of chemicals in dust by applying a combination of target, suspect screening, and non-target methods with mass spectrometry preceded by liquid chromatography and gas chromatography. Building upon a previous study that detected 271 compounds in 38 dust samples, we presented concentrations of 144 compounds that were confirmed and quantified by standards in the same set of samples. Ten compounds were measured with median concentrations greater than 10 000 ng/g of dust: cis-hexadec-6-enoic acid, squalene, cholesterol, vitamin E, bis(2-ethylhexyl) phthalate, dioctyl terephthalate, linoleic acid, tricaprylin, tris(1-chloroisopropyl) phosphate, and oxybenzone. We also reviewed in vitro toxicity screening data to identify compounds that were not previously detected in indoor dust but have potential for adverse health effects. Among 119 newly detected compounds, 13 had endocrine-disrupting potential and 7 had neurotoxic potential. Toxicity screening data were not available for eight biocides, which may adversely affect health. Our results strive to provide more comprehensive chemical profiles of house dust and identified information gaps for future health studies.

Original languageEnglish (US)
JournalIndoor Air
DOIs
StateAccepted/In press - Jan 1 2019

Fingerprint

Consumer products
Dust
Toxicity
Screening
Health
Diethylhexyl Phthalate
Squalene
Linoleic acid
Biocides
Disinfectants
Vitamins
Cholesterol
Liquid chromatography
Linoleic Acid
Vitamin E
Liquid Chromatography
Gas chromatography
Gas Chromatography
Mass spectrometry
Mass Spectrometry

Keywords

  • concentration
  • dust
  • in vitro bioactivity assays
  • non-target
  • suspect screening
  • target

ASJC Scopus subject areas

  • Environmental Engineering
  • Building and Construction
  • Public Health, Environmental and Occupational Health

Cite this

Measured concentrations of consumer product chemicals in California house dust : Implications for sources, exposure, and toxicity potential. / Shin, Hyeong Moo; Moschet, Christoph; Young, Thomas M.; Bennett, Deborah H.

In: Indoor Air, 01.01.2019.

Research output: Contribution to journalArticle

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