MaxPET: A dedicated mammary and axillary region positron emission tomography imaging system for breast cancer

N. K. Doshi, R. W. Silverman, Y. Shao, Simon R Cherry

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

We have built a dedicated PET system for breast cancer patient imaging. The modular detector is composed of a 9×9 array of 3×3×20 mm LSO scintillator crystals coupled to an optical fiber taper, which in turn is coupled to a Hamamatsu R5900-C8 position-sensitive photomultiplier tube. Two modules have been characterized with the following results: average intrinsic spatial resolution = 2.26 mm, average energy resolution = 19.5% at 511 keV, coincidence time resolution = 2.4 ns, and detector efficiency = 53% using a 350 keV energy threshold. To create the maxPET system, we have tiled 50 of these modular detectors into 5×5 arrays forming two parallel detector plates measuring 15cm × 15cm. Using a multiplexed sector readout scheme we have obtained singles flood histograms allowing identification of >90% of the 2025 crystals in each plate without any optimization. We are in the process of improving the crystal look-up tables and will fully characterize the complete imaging system. The data is acquired in projection mode or by rotating the plates to obtain tomographic datasets. The promising results from the individual detector modules support the feasibility of developing a high resolution, high sensitivity dedicated PET system for breast cancer applications.

Original languageEnglish (US)
Title of host publicationIEEE Nuclear Science Symposium and Medical Imaging Conference
EditorsD. Merelli, J. Surget, M. Ulma
Volume3
StatePublished - 2000
Event2000 IEEE Nuclear Science Symposium Conference Record - Lyon, France
Duration: Oct 15 2000Oct 20 2000

Other

Other2000 IEEE Nuclear Science Symposium Conference Record
CountryFrance
CityLyon
Period10/15/0010/20/00

ASJC Scopus subject areas

  • Computer Vision and Pattern Recognition
  • Industrial and Manufacturing Engineering

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  • Cite this

    Doshi, N. K., Silverman, R. W., Shao, Y., & Cherry, S. R. (2000). MaxPET: A dedicated mammary and axillary region positron emission tomography imaging system for breast cancer. In D. Merelli, J. Surget, & M. Ulma (Eds.), IEEE Nuclear Science Symposium and Medical Imaging Conference (Vol. 3)