Maximal growth occurs at a broad range of essential amino acids to total nitrogen ratios in kittens

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5 Scopus citations

Abstract

Kittens fed diets containing 2.0 and 3.0 times (x) the NRC essential amino acid (EAA) requirement (EAArq) and 210 to 560 g crude protein (CP)/kg diet had growth rates and plasma amino acid patterns that were not significantly different than kittens fed a control diet (CD) containing 1.5 x EAArq and 350 g CP/kg diet. Growth rates of kittens fed diets containing only EAA (with nontoxic levels of arginine and methionine) and 280 to 460 g CP/kg diet were equivalent to those of kittens fed CD. Kittens fed only EAA and 140 and 210g CP/kg diet had growth rates that were significantly lower than kittens fed CD. Since the growth rate of kittens fed 1.5 x EAArq and 210g CP/kg diet in a previous experiment was equivalent to kittens fed CD it is suggested that the requirement for CP is higher (up to 280 g CP/kg diet) when only EAA are fed. The higher crude protein requirement appears to be primarily a consequence of the high obligatory nitrogen loss as urea (especially from arginine) incurred in the conversion of nitrogen from EAA to dispensable amino acids in the liver and secondarily because of a slow rate of catabolism of the EAA. A 3-dimensional plot of weight gains vs. CP levels and EAA to total nitrogen (E:T) ratios of kittens shows a broad range of CP levels and E:T ratios that support optimal growth in the kitten. It is suggested that similar patterns would occur in the chick, rat and other species if adverse effects caused by excesses of specific amino acids are avoided.

Original languageEnglish (US)
Pages (from-to)221-234
Number of pages14
JournalAmino Acids
Volume15
Issue number3
StatePublished - 1998

Keywords

  • Amino acids
  • Crude protein
  • Dispensable amino acids
  • Essential amino acids
  • Feline
  • Kittens

ASJC Scopus subject areas

  • Clinical Biochemistry
  • Biochemistry
  • Endocrinology

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