Mastocytosis: The great masquerader

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Variants of mastocytosis can present with puzzling cutaneous and systemic symptoms and signs that can result in an erroneous diagnosis of idiopathic urticaria or idiopathic anayphylaxis. The molecular basis of mastocytosis is now better understood, with updated classification based on distinct growth factor and oncogene abnormalities. Elicitation of a full history and careful attention to the skin examination will usually provide the clinician enough information to deduce that the condition is not simply chronic idiopathic urticaria.

Original languageEnglish (US)
Pages (from-to)53-60
Number of pages8
JournalClinical Reviews in Allergy and Immunology
Volume30
Issue number1
StatePublished - Feb 2006

Fingerprint

Mastocytosis
Urticaria
Skin
Oncogenes
Signs and Symptoms
Intercellular Signaling Peptides and Proteins
History

Keywords

  • c-kit gene mutation
  • Drug allergy
  • Mast cell
  • Tryptase
  • Urticaria pigmentosa

ASJC Scopus subject areas

  • Immunology and Allergy

Cite this

Mastocytosis : The great masquerader. / Kong, James S W; Teuber, Suzanne S; Hallett, Rosemary L; Gershwin, M. Eric.

In: Clinical Reviews in Allergy and Immunology, Vol. 30, No. 1, 02.2006, p. 53-60.

Research output: Contribution to journalArticle

@article{1b1d002ea4644e1abe9c1a66a4c71b76,
title = "Mastocytosis: The great masquerader",
abstract = "Variants of mastocytosis can present with puzzling cutaneous and systemic symptoms and signs that can result in an erroneous diagnosis of idiopathic urticaria or idiopathic anayphylaxis. The molecular basis of mastocytosis is now better understood, with updated classification based on distinct growth factor and oncogene abnormalities. Elicitation of a full history and careful attention to the skin examination will usually provide the clinician enough information to deduce that the condition is not simply chronic idiopathic urticaria.",
keywords = "c-kit gene mutation, Drug allergy, Mast cell, Tryptase, Urticaria pigmentosa",
author = "Kong, {James S W} and Teuber, {Suzanne S} and Hallett, {Rosemary L} and Gershwin, {M. Eric}",
year = "2006",
month = "2",
language = "English (US)",
volume = "30",
pages = "53--60",
journal = "Clinical Reviews in Allergy and Immunology",
issn = "1080-0549",
publisher = "Humana Press",
number = "1",

}

TY - JOUR

T1 - Mastocytosis

T2 - The great masquerader

AU - Kong, James S W

AU - Teuber, Suzanne S

AU - Hallett, Rosemary L

AU - Gershwin, M. Eric

PY - 2006/2

Y1 - 2006/2

N2 - Variants of mastocytosis can present with puzzling cutaneous and systemic symptoms and signs that can result in an erroneous diagnosis of idiopathic urticaria or idiopathic anayphylaxis. The molecular basis of mastocytosis is now better understood, with updated classification based on distinct growth factor and oncogene abnormalities. Elicitation of a full history and careful attention to the skin examination will usually provide the clinician enough information to deduce that the condition is not simply chronic idiopathic urticaria.

AB - Variants of mastocytosis can present with puzzling cutaneous and systemic symptoms and signs that can result in an erroneous diagnosis of idiopathic urticaria or idiopathic anayphylaxis. The molecular basis of mastocytosis is now better understood, with updated classification based on distinct growth factor and oncogene abnormalities. Elicitation of a full history and careful attention to the skin examination will usually provide the clinician enough information to deduce that the condition is not simply chronic idiopathic urticaria.

KW - c-kit gene mutation

KW - Drug allergy

KW - Mast cell

KW - Tryptase

KW - Urticaria pigmentosa

UR - http://www.scopus.com/inward/record.url?scp=32044474643&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=32044474643&partnerID=8YFLogxK

M3 - Article

C2 - 16461996

AN - SCOPUS:32044474643

VL - 30

SP - 53

EP - 60

JO - Clinical Reviews in Allergy and Immunology

JF - Clinical Reviews in Allergy and Immunology

SN - 1080-0549

IS - 1

ER -