Mastocytosis: The great masquerader

Research output: Contribution to journalArticle

7 Scopus citations

Abstract

Variants of mastocytosis can present with puzzling cutaneous and systemic symptoms and signs that can result in an erroneous diagnosis of idiopathic urticaria or idiopathic anayphylaxis. The molecular basis of mastocytosis is now better understood, with updated classification based on distinct growth factor and oncogene abnormalities. Elicitation of a full history and careful attention to the skin examination will usually provide the clinician enough information to deduce that the condition is not simply chronic idiopathic urticaria.

Original languageEnglish (US)
Pages (from-to)53-60
Number of pages8
JournalClinical Reviews in Allergy and Immunology
Volume30
Issue number1
StatePublished - Feb 2006

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Keywords

  • c-kit gene mutation
  • Drug allergy
  • Mast cell
  • Tryptase
  • Urticaria pigmentosa

ASJC Scopus subject areas

  • Immunology and Allergy

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