Mast cell tumors in a llama (Lama glama)

Tzu-Yin Lin, Alexander Hamberg, Rebecca Pentecost, Maxey Wellman, Paul Stromberg

Research output: Contribution to journalArticlepeer-review

10 Scopus citations


A 9-year-old female llama (Lama glama) that served as a blood donor at The Ohio State University Veterinary Teaching Hospital developed multiple small, raised, firm, non-haired cutaneous masses on the right hip, left cheek, and right and left shoulders. Cytological evaluation of fine-needle aspirates from the cutaneous mass from the left shoulder and right hip comprised many well-differentiated, highly granulated mast cells with moderate numbers of eosinophils. Occasional mast cells exhibited erythrophagocytosis and contained a small amount of hemosiderin or several variably sized vacuoles. A cytologic diagnosis of mast cell tumor with evidence of prior hemorrhage was made, and the masses were surgically removed. Microscopically, each mass consisted of sheets of neoplastic round cells that formed nonencapsulated nodules in the dermis and infiltrated into the adjacent dermal collagen. Eosinophils were scattered among the mast cells at the periphery of the nodules. Neoplastic mast cells, but not eosinophils, exhibited positive membrane KIT expression and cytoplasmic vimentin staining. A final diagnosis of mast cell tumor was made based on cytology, histology, and immunohistochemistry.

Original languageEnglish (US)
Pages (from-to)808-811
Number of pages4
JournalJournal of Veterinary Diagnostic Investigation
Issue number5
StatePublished - Jan 1 2010
Externally publishedYes


  • KIT
  • Llamas
  • Mast cell tumors

ASJC Scopus subject areas

  • veterinary(all)


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